We narrowed to 2 results for: hyper

...depolarization) of the neuron. Inhibitory (hyperpolarizing) ChR variants Anion-conducting ChR variants...chloride channels, these variants result in the hyperpolarization of neurons. Examples of anion channel variants...NpHR (from Natronomonas pharaoni ), causes hyperpolarization (inhibition) of the cell when triggered with... a light-activated outward proton pump that hyperpolarizes (inhibits) the cell when triggered by green-yellow... robust optogenetic inhibitors that act by hyperpolarizing cells via high K + efflux. Synthetic light-...

...spectrum of single-nucleotide variants (somatic hypermutation) in a larger editing window. These systems are...REPAIR , developed by the Feng Zhang lab , used a hyperactive adenosine deaminase that acts on RNA, ADAR2(E488Q...Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells. Nature Methods . 13 (12)...