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pCMV_ABEmax_P2A_GFP Citations (27)

Originally described in: Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction.
Koblan LW, Doman JL, Wilson C, Levy JM, Tay T, Newby GA, Maianti JP, Raguram A, Liu DR Nat Biotechnol. 2018 May 29. pii: nbt.4172. doi: 10.1038/nbt.4172. PubMed Journal

Articles Citing pCMV_ABEmax_P2A_GFP

Articles
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors. Grunewald J, Zhou R, Garcia SP, Iyer S, Lareau CA, Aryee MJ, Joung JK. Nature. 2019 Apr 17. pii: 10.1038/s41586-019-1161-z. doi: 10.1038/s41586-019-1161-z. PubMed

Associated Plasmids
CRISPR DNA base editors with reduced RNA off-target and self-editing activities. Grunewald J, Zhou R, Iyer S, Lareau CA, Garcia SP, Aryee MJ, Joung JK. Nat Biotechnol. 2019 Sep 2. pii: 10.1038/s41587-019-0236-6. doi: 10.1038/s41587-019-0236-6. PubMed

Associated Plasmids
Modeling Niemann-Pick disease type C in a human haploid cell line allows for patient variant characterization and clinical interpretation. Erwood S, Brewer RA, Bily TMI, Maino E, Zhou L, Cohn RD, Ivakine EA. Genome Res. 2019 Dec;29(12):2010-2019. doi: 10.1101/gr.250720.119. Epub 2019 Nov 21. PubMed

Associated Plasmids
A compact Cas9 ortholog from Staphylococcus Auricularis (SauriCas9) expands the DNA targeting scope. Hu Z, Wang S, Zhang C, Gao N, Li M, Wang D, Wang D, Liu D, Liu H, Ong SG, Wang H, Wang Y. PLoS Biol. 2020 Mar 30;18(3):e3000686. doi: 10.1371/journal.pbio.3000686. eCollection 2020 Mar. PubMed

Associated Plasmids
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing. Grunewald J, Zhou R, Lareau CA, Garcia SP, Iyer S, Miller BR, Langner LM, Hsu JY, Aryee MJ, Joung JK. Nat Biotechnol. 2020 Jun 1. pii: 10.1038/s41587-020-0535-y. doi: 10.1038/s41587-020-0535-y. PubMed

Associated Plasmids
CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells. Kurt IC, Zhou R, Iyer S, Garcia SP, Miller BR, Langner LM, Grunewald J, Joung JK. Nat Biotechnol. 2020 Jul 20. pii: 10.1038/s41587-020-0609-x. doi: 10.1038/s41587-020-0609-x. PubMed

Associated Plasmids
Discovery and engineering of small SlugCas9 with broad targeting range and high specificity and activity. Hu Z, Zhang C, Wang S, Gao S, Wei J, Li M, Hou L, Mao H, Wei Y, Qi T, Liu H, Liu D, Lan F, Lu D, Wang H, Li J, Wang Y. Nucleic Acids Res. 2021 Mar 15. pii: 6171296. doi: 10.1093/nar/gkab148. PubMed

Associated Plasmids
Precise correction of Duchenne muscular dystrophy exon deletion mutations by base and prime editing. Chemello F, Chai AC, Li H, Rodriguez-Caycedo C, Sanchez-Ortiz E, Atmanli A, Mireault AA, Liu N, Bassel-Duby R, Olson EN. Sci Adv. 2021 Apr 30;7(18). pii: 7/18/eabg4910. doi: 10.1126/sciadv.abg4910. Print 2021 Apr. PubMed
Single-nucleotide-level mapping of DNA regulatory elements that control fetal hemoglobin expression. Cheng L, Li Y, Qi Q, Xu P, Feng R, Palmer L, Chen J, Wu R, Yee T, Zhang J, Yao Y, Sharma A, Hardison RC, Weiss MJ, Cheng Y. Nat Genet. 2021 Jun;53(6):869-880. doi: 10.1038/s41588-021-00861-8. Epub 2021 May 6. PubMed
STAT1 gain-of-function heterozygous cell models reveal diverse interferon-signature gene transcriptional responses. Scott O, Lindsay K, Erwood S, Mollica A, Roifman CM, Cohn RD, Ivakine EA. NPJ Genom Med. 2021 May 14;6(1):34. doi: 10.1038/s41525-021-00196-7. PubMed
In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels. Rothgangl T, Dennis MK, Lin PJC, Oka R, Witzigmann D, Villiger L, Qi W, Hruzova M, Kissling L, Lenggenhager D, Borrelli C, Egli S, Frey N, Bakker N, Walker JA 2nd, Kadina AP, Victorov DV, Pacesa M, Kreutzer S, Kontarakis Z, Moor A, Jinek M, Weissman D, Stoffel M, van Boxtel R, Holden K, Pardi N, Thony B, Haberle J, Tam YK, Semple SC, Schwank G. Nat Biotechnol. 2021 Aug;39(8):949-957. doi: 10.1038/s41587-021-00933-4. Epub 2021 May 19. PubMed
Adenine base editor engineering reduces editing of bystander cytosines. Jeong YK, Lee S, Hwang GH, Hong SA, Park SE, Kim JS, Woo JS, Bae S. Nat Biotechnol. 2021 Nov;39(11):1426-1433. doi: 10.1038/s41587-021-00943-2. Epub 2021 Jul 1. PubMed
Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids. Geurts MH, de Poel E, Pleguezuelos-Manzano C, Oka R, Carrillo L, Andersson-Rolf A, Boretto M, Brunsveld JE, van Boxtel R, Beekman JM, Clevers H. Life Sci Alliance. 2021 Aug 9;4(10). pii: 4/10/e202000940. doi: 10.26508/lsa.202000940. Print 2021 Oct. PubMed
Predicting base editing outcomes with an attention-based deep learning algorithm trained on high-throughput target library screens. Marquart KF, Allam A, Janjuha S, Sintsova A, Villiger L, Frey N, Krauthammer M, Schwank G. Nat Commun. 2021 Aug 25;12(1):5114. doi: 10.1038/s41467-021-25375-z. PubMed
Adenine base editing of the DUX4 polyadenylation signal for targeted genetic therapy in facioscapulohumeral muscular dystrophy. Sikrova D, Cadar VA, Ariyurek Y, Laros JFJ, Balog J, van der Maarel SM. Mol Ther Nucleic Acids. 2021 Jun 1;25:342-354. doi: 10.1016/j.omtn.2021.05.020. eCollection 2021 Sep 3. PubMed
Saturation variant interpretation using CRISPR prime editing. Erwood S, Bily TMI, Lequyer J, Yan J, Gulati N, Brewer RA, Zhou L, Pelletier L, Ivakine EA, Cohn RD. Nat Biotechnol. 2022 Jun;40(6):885-895. doi: 10.1038/s41587-021-01201-1. Epub 2022 Feb 21. PubMed
Targeting double-strand break indel byproducts with secondary guide RNAs improves Cas9 HDR-mediated genome editing efficiencies. Bodai Z, Bishop AL, Gantz VM, Komor AC. Nat Commun. 2022 May 9;13(1):2351. doi: 10.1038/s41467-022-29989-9. PubMed
Transient expression of an adenine base editor corrects the Hutchinson-Gilford progeria syndrome mutation and improves the skin phenotype in mice. Whisenant D, Lim K, Revechon G, Yao H, Bergo MO, Machtel P, Kim JS, Eriksson M. Nat Commun. 2022 Jun 2;13(1):3068. doi: 10.1038/s41467-022-30800-y. PubMed
Cloning and base editing of GFP transgenic rhesus monkey and off-target analysis. Kang Y, Dai S, Zeng Y, Wang F, Yang P, Yang Z, Pu Y, Li Z, Chen X, Tian B, Si W, Ji W, Niu Y. Sci Adv. 2022 Jul 22;8(29):eabo3123. doi: 10.1126/sciadv.abo3123. Epub 2022 Jul 22. PubMed
Examination of the Cell Cycle Dependence of Cytosine and Adenine Base Editors. Burnett CA, Wong AT, Vasquez CA, McHugh CA, Yeo GW, Komor AC. Front Genome Ed. 2022 Jul 14;4:923718. doi: 10.3389/fgeed.2022.923718. eCollection 2022. PubMed
Adenine base editing efficiently restores the function of Fanconi anemia hematopoietic stem and progenitor cells. Siegner SM, Ugalde L, Clemens A, Garcia-Garcia L, Bueren JA, Rio P, Karasu ME, Corn JE. Nat Commun. 2022 Nov 12;13(1):6900. doi: 10.1038/s41467-022-34479-z. PubMed
The Wild-Type tRNA Adenosine Deaminase Enzyme TadA Is Capable of Sequence-Specific DNA Base Editing. Ranzau BL, Rallapalli KL, Evanoff M, Paesani F, Komor AC. Chembiochem. 2023 Aug 15;24(16):e202200788. doi: 10.1002/cbic.202200788. Epub 2023 May 24. PubMed
Retrotransposon LINE-1 bodies in the cytoplasm of piRNA-deficient mouse spermatocytes: Ribonucleoproteins overcoming the integrated stress response. De Luca C, Gupta A, Bortvin A. PLoS Genet. 2023 Jun 12;19(6):e1010797. doi: 10.1371/journal.pgen.1010797. eCollection 2023 Jun. PubMed
CRISPR single base-editing: in silico predictions to variant clonal cell lines. Dickson KA, Field N, Blackman T, Ma Y, Xie T, Kurangil E, Idrees S, Rathnayake SNH, Mahbub RM, Faiz A, Marsh DJ. Hum Mol Genet. 2023 Jun 27:ddad105. doi: 10.1093/hmg/ddad105. PubMed
One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids. Geurts MH, Gandhi S, Boretto MG, Akkerman N, Derks LLM, van Son G, Celotti M, Harshuk-Shabso S, Peci F, Begthel H, Hendriks D, Schurmann P, Andersson-Rolf A, Chuva de Sousa Lopes SM, van Es JH, van Boxtel R, Clevers H. Nat Commun. 2023 Aug 17;14(1):4998. doi: 10.1038/s41467-023-40701-3. PubMed
Prediction of base editor off-targets by deep learning. Zhang C, Yang Y, Qi T, Zhang Y, Hou L, Wei J, Yang J, Shi L, Ong SG, Wang H, Wang H, Yu B, Wang Y. Nat Commun. 2023 Sep 2;14(1):5358. doi: 10.1038/s41467-023-41004-3. PubMed
Direct measurement of engineered cancer mutations and their transcriptional phenotypes in single cells. Kim HS, Grimes SM, Chen T, Sathe A, Lau BT, Hwang GH, Bae S, Ji HP. Nat Biotechnol. 2023 Sep 11. doi: 10.1038/s41587-023-01949-8. PubMed

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