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FUW-M2rtTA Citations (55)

Plasmid Article: A drug-inducible system for direct reprogramming of human somatic cells to pluripotency.
Hockemeyer D, Soldner F, Cook EG, Gao Q, Mitalipova M, Jaenisch R Cell Stem Cell. 2008 Sep 11. 3(3):346-53.
PubMed Journal

Articles Citing FUW-M2rtTA

Leukemia inhibitory factor (LIF)-dependent, pluripotent stem cells established from inner cell mass of porcine embryos. Telugu BP, Ezashi T, Sinha S, Alexenko AP, Spate L, Prather RS, Roberts RM. J Biol Chem. 2011 Aug 19;286(33):28948-53. doi: 10.1074/jbc.M111.229468. Epub 2011 Jun 24. PubMed
Genetic background affects induced pluripotent stem cell generation. Schnabel LV, Abratte CM, Schimenti JC, Southard TL, Fortier LA. Stem Cell Res Ther. 2012 Aug 3;3(4):30. doi: 10.1186/scrt121. PubMed
Elevating SOX2 levels deleteriously affects the growth of medulloblastoma and glioblastoma cells. Cox JL, Wilder PJ, Desler M, Rizzino A. PLoS One. 2012;7(8):e44087. doi: 10.1371/journal.pone.0044087. Epub 2012 Aug 28. PubMed
Sirtuin 1 facilitates generation of induced pluripotent stem cells from mouse embryonic fibroblasts through the miR-34a and p53 pathways. Lee YL, Peng Q, Fong SW, Chen AC, Lee KF, Ng EH, Nagy A, Yeung WS. PLoS One. 2012;7(9):e45633. doi: 10.1371/journal.pone.0045633. Epub 2012 Sep 21. PubMed
Predicting stem cell fate changes by differential cell cycle progression patterns. Roccio M, Schmitter D, Knobloch M, Okawa Y, Sage D, Lutolf MP. Development. 2013 Jan 15;140(2):459-70. doi: 10.1242/dev.086215. Epub 2012 Nov 28. PubMed
Barcoding cells using cell-surface programmable DNA-binding domains. Mali P, Aach J, Lee JH, Levner D, Nip L, Church GM. Nat Methods. 2013 Mar 17. doi: 10.1038/nmeth.2407. PubMed

Associated Plasmids

Neural progenitor cell survival in mouse brain can be improved by co-transplantation of helper cells expressing bFGF under doxycycline control. Liang Y, Agren L, Lyczek A, Walczak P, Bulte JW. Exp Neurol. 2013 Sep;247:73-9. doi: 10.1016/j.expneurol.2013.04.001. Epub 2013 Apr 6. PubMed
Regulation of anoikis by deleted in breast cancer-1 (DBC1) through NF-kappaB. Park SH, Riley P 4th, Frisch SM. Apoptosis. 2013 Aug;18(8):949-62. doi: 10.1007/s10495-013-0847-1. PubMed
Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming. Christoforou N, Chellappan M, Adler AF, Kirkton RD, Wu T, Addis RC, Bursac N, Leong KW. PLoS One. 2013 May 21;8(5):e63577. doi: 10.1371/journal.pone.0063577. Print 2013. PubMed
NGF upregulates the plasminogen activation inhibitor-1 in neurons via the calcineurin/NFAT pathway and the Down syndrome-related proteins DYRK1A and RCAN1 attenuate this effect. Stefos GC, Soppa U, Dierssen M, Becker W. PLoS One. 2013 Jun 25;8(6):e67470. doi: 10.1371/journal.pone.0067470. Print 2013. PubMed
Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system. Cheng AW, Wang H, Yang H, Shi L, Katz Y, Theunissen TW, Rangarajan S, Shivalila CS, Dadon DB, Jaenisch R. Cell Res. 2013 Aug 27. doi: 10.1038/cr.2013.122. PubMed

Associated Plasmids

Identification of epithelial stromal interaction 1 as a novel effector downstream of Kruppel-like factor 8 in breast cancer invasion and metastasis. Li T, Lu H, Shen C, Lahiri SK, Wason MS, Mukherjee D, Yu L, Zhao J. Oncogene. 2014 Sep 25;33(39):4746-55. doi: 10.1038/onc.2013.415. Epub 2013 Oct 7. PubMed
Increased expression of S100A6 promotes cell proliferation and migration in human hepatocellular carcinoma. Li Z, Tang M, Ling B, Liu S, Zheng Y, Nie C, Yuan Z, Zhou L, Guo G, Tong A, Wei Y. J Mol Med (Berl). 2014 Mar;92(3):291-303. doi: 10.1007/s00109-013-1104-3. Epub 2013 Nov 27. PubMed
Overlap of Doxycycline Fluorescence with that of the Redox-Sensitive Intracellular Reporter roGFP. Khader H, Solodushko V, Al-Mehdi AB, Audia J, Fouty B. J Fluoresc. 2013 Nov 28. PubMed
Matrix identity and tractional forces influence indirect cardiac reprogramming. Kong YP, Carrion B, Singh RK, Putnam AJ. Sci Rep. 2013 Dec 11;3:3474. doi: 10.1038/srep03474. PubMed

Associated Plasmids

Counteracting activities of OCT4 and KLF4 during reprogramming to pluripotency. Tiemann U, Marthaler AG, Adachi K, Wu G, Fischedick GU, Arauzo-Bravo MJ, Scholer HR, Tapia N. Stem Cell Reports. 2014 Feb 20;2(3):351-65. doi: 10.1016/j.stemcr.2014.01.005. eCollection 2014 Mar 11. PubMed
The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons. Kulangara K, Adler AF, Wang H, Chellappan M, Hammett E, Yasuda R, Leong KW. Biomaterials. 2014 Jul;35(20):5327-36. doi: 10.1016/j.biomaterials.2014.03.034. Epub 2014 Apr 4. PubMed
Transdifferentiation of mouse fibroblasts and hepatocytes to functional neurons. Marro S, Yang N. Methods Mol Biol. 2014;1150:237-46. doi: 10.1007/978-1-4939-0512-6_16. PubMed
The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation. Soppa U, Schumacher J, Florencio Ortiz V, Pasqualon T, Tejedor FJ, Becker W. Cell Cycle. 2014;13(13):2084-100. doi: 10.4161/cc.29104. Epub 2014 May 7. PubMed
lincRNA-RoR and miR-145 regulate invasion in triple-negative breast cancer via targeting ARF6. Eades G, Wolfson B, Zhang Y, Li Q, Yao Y, Zhou Q. Mol Cancer Res. 2015 Feb;13(2):330-8. doi: 10.1158/1541-7786.MCR-14-0251. Epub 2014 Sep 24. PubMed
Cell divisions are not essential for the direct conversion of fibroblasts into neuronal cells. Fishman VS, Shnayder TA, Orishchenko KE, Bader M, Alenina N, Serov OL. Cell Cycle. 2015;14(8):1188-96. doi: 10.1080/15384101.2015.1012875. PubMed
Stemness factor Sall4 is required for DNA damage response in embryonic stem cells. Xiong J, Todorova D, Su NY, Kim J, Lee PJ, Shen Z, Briggs SP, Xu Y. J Cell Biol. 2015 Mar 2;208(5):513-20. doi: 10.1083/jcb.201408106. PubMed
Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. Shi Y, Chen J, Karner CM, Long F. Proc Natl Acad Sci U S A. 2015 Apr 14;112(15):4678-83. doi: 10.1073/pnas.1502301112. Epub 2015 Mar 30. PubMed
Derivation of LIF-independent mouse iPS cells with modified Oct4. Hirai H, Firpo M, Kikyo N. Stem Cell Res. 2015 Sep;15(2):384-6. doi: 10.1016/j.scr.2015.08.005. Epub 2015 Aug 17. PubMed
Establishment of leukemia inhibitory factor (LIF)-independent iPS cells with potentiated Oct4. Hirai H, Firpo M, Kikyo N. Stem Cell Res. 2015 Nov;15(3):469-80. doi: 10.1016/j.scr.2015.09.002. Epub 2015 Sep 12. PubMed
Phosphatidic Acid Improves Reprogramming to Pluripotency by Reducing Apoptosis. Jiang Y, Du M, Wu M, Zhu Y, Zhao X, Cao X, Li X, Long P, Li W, Hu B. Stem Cells Dev. 2016 Jan 1;25(1):43-54. doi: 10.1089/scd.2015.0159. Epub 2015 Nov 10. PubMed
Derivation of Ethnically Diverse Human Induced Pluripotent Stem Cell Lines. Chang EA, Tomov ML, Suhr ST, Luo J, Olmsted ZT, Paluh JL, Cibelli J. Sci Rep. 2015 Oct 20;5:15234. doi: 10.1038/srep15234. PubMed
Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation. McDonald JI, Celik H, Rois LE, Fishberger G, Fowler T, Rees R, Kramer A, Martens A, Edwards JR, Challen GA. Biol Open. 2016 May 11. pii: bio.019067. doi: 10.1242/bio.019067. PubMed

Associated Plasmids

MYC Is a Crucial Mediator of TGFbeta-Induced Invasion in Basal Breast Cancer. Cichon MA, Moruzzi ME, Shqau TA, Miller E, Mehner C, Ethier SP, Copland JA, Radisky ES, Radisky DC. Cancer Res. 2016 Jun 15;76(12):3520-30. doi: 10.1158/0008-5472.CAN-15-3465. Epub 2016 Apr 13. PubMed
Efficient generation of dopaminergic-like neurons by overexpression of Nurr1 and Pitx3 in mouse induced Pluripotent Stem Cells. Salemi S, Baktash P, Rajaei B, Noori M, Amini H, Shamsara M, Massumi M. Neurosci Lett. 2016 Jul 28;626:126-34. doi: 10.1016/j.neulet.2016.05.032. Epub 2016 May 18. PubMed
Forced expression of Hnf4a induces hepatic gene activation through directed differentiation. Yahoo N, Pournasr B, Rostamzadeh J, Fathi F. Biochem Biophys Res Commun. 2016 Aug 5;476(4):313-8. doi: 10.1016/j.bbrc.2016.05.119. Epub 2016 May 24. PubMed
Pancreatic Endoderm-Derived from Diabetic Patient-Specific Induced Pluripotent Stem Cell Generates Glucose-Responsive Insulin-Secreting Cells. Rajaei B, Shamsara M, Fakhr Taha M, Massumi M, Sanati MH. J Cell Physiol. 2016 Jun 16. doi: 10.1002/jcp.25459. PubMed
TRIM28 is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming. Miles DC, de Vries NA, Gisler S, Lieftink C, Akhtar W, Gogola E, Pawlitzky I, Hulsman D, Tanger E, Koppens M, Beijersbergen RL, van Lohuizen M. Stem Cells. 2017 Jan;35(1):147-157. doi: 10.1002/stem.2453. Epub 2016 Jul 6. PubMed
A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease. Villaescusa JC, Li B, Toledo EM, Rivetti di Val Cervo P, Yang S, Stott SR, Kaiser K, Islam S, Gyllborg D, Laguna-Goya R, Landreh M, Lonnerberg P, Falk A, Bergman T, Barker RA, Linnarsson S, Selleri L, Arenas E. EMBO J. 2016 Sep 15;35(18):1963-78. doi: 10.15252/embj.201593725. Epub 2016 Jun 28. PubMed
Direct Induction and Functional Maturation of Forebrain GABAergic Neurons from Human Pluripotent Stem Cells. Sun AX, Yuan Q, Tan S, Xiao Y, Wang D, Khoo AT, Sani L, Tran HD, Kim P, Chiew YS, Lee KJ, Yen YC, Ng HH, Lim B, Je HS. Cell Rep. 2016 Aug 16;16(7):1942-53. doi: 10.1016/j.celrep.2016.07.035. Epub 2016 Aug 4. PubMed
Emerin suppresses Notch signaling by restricting the Notch intracellular domain to the nuclear membrane. Lee B, Lee TH, Shim J. Biochim Biophys Acta. 2017 Feb;1864(2):303-313. doi: 10.1016/j.bbamcr.2016.11.013. Epub 2016 Nov 16. PubMed
Nipbl Interacts with Zfp609 and the Integrator Complex to Regulate Cortical Neuron Migration. van den Berg DL, Azzarelli R, Oishi K, Martynoga B, Urban N, Dekkers DH, Demmers JA, Guillemot F. Neuron. 2016 Dec 20. pii: S0896-6273(16)30915-1. doi: 10.1016/j.neuron.2016.11.047. PubMed
Reprogramming Mouse Embryonic Fibroblasts with Transcription Factors to Induce a Hemogenic Program. Daniel MG, Pereira CF, Bernitz JM, Lemischka IR, Moore K. J Vis Exp. 2016 Dec 16;(118). doi: 10.3791/54372. PubMed
Core Transcription Factors, MicroRNAs, and Small Molecules Drive Transdifferentiation of Human Fibroblasts Towards The Cardiac Cell Lineage. Christoforou N, Chakraborty S, Kirkton RD, Adler AF, Addis RC, Leong KW. Sci Rep. 2017 Jan 10;7:40285. doi: 10.1038/srep40285. PubMed
Highly Expandable Human iPS Cell-Derived Neural Progenitor Cells (NPC) and Neurons for Central Nervous System Disease Modeling and High-Throughput Screening. Cheng C, Fass DM, Folz-Donahue K, MacDonald ME, Haggarty SJ. Curr Protoc Hum Genet. 2017 Jan 11;92:21.8.1-21.8.21. doi: 10.1002/cphg.33. PubMed
Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease. Chao MP, Gentles AJ, Chatterjee S, Lan F, Reinisch A, Corces MR, Xavy S, Shen J, Haag D, Chanda S, Sinha R, Morganti RM, Nishimura T, Ameen M, Wu H, Wernig M, Wu JC, Majeti R. Cell Stem Cell. 2017 Mar 2;20(3):329-344.e7. doi: 10.1016/j.stem.2016.11.018. Epub 2017 Jan 12. PubMed
Enhanced Cardiac Differentiation of Human Cardiovascular Disease Patient-Specific Induced Pluripotent Stem Cells by Applying Unidirectional Electrical Pulses Using Aligned Electroactive Nanofibrous Scaffolds. Mohammadi Amirabad L, Massumi M, Shamsara M, Shabani I, Amari A, Mossahebi Mohammadi M, Hosseinzadeh S, Vakilian S, Steinbach SK, Khorramizadeh MR, Soleimani M, Barzin J. ACS Appl Mater Interfaces. 2017 Mar 1;9(8):6849-6864. doi: 10.1021/acsami.6b15271. Epub 2017 Feb 15. PubMed
Interspecies Chimerism with Mammalian Pluripotent Stem Cells. Wu J, Platero-Luengo A, Sakurai M, Sugawara A, Gil MA, Yamauchi T, Suzuki K, Bogliotti YS, Cuello C, Morales Valencia M, Okumura D, Luo J, Vilarino M, Parrilla I, Soto DA, Martinez CA, Hishida T, Sanchez-Bautista S, Martinez-Martinez ML, Wang H, Nohalez A, Aizawa E, Martinez-Redondo P, Ocampo A, Reddy P, Roca J, Maga EA, Esteban CR, Berggren WT, Nunez Delicado E, Lajara J, Guillen I, Guillen P, Campistol JM, Martinez EA, Ross PJ, Izpisua Belmonte JC. Cell. 2017 Jan 26;168(3):473-486.e15. doi: 10.1016/j.cell.2016.12.036. PubMed
Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors. Ehrlich M, Mozafari S, Glatza M, Starost L, Velychko S, Hallmann AL, Cui QL, Schambach A, Kim KP, Bachelin C, Marteyn A, Hargus G, Johnson RM, Antel J, Sterneckert J, Zaehres H, Scholer HR, Baron-Van Evercooren A, Kuhlmann T. Proc Natl Acad Sci U S A. 2017 Mar 14;114(11):E2243-E2252. doi: 10.1073/pnas.1614412114. Epub 2017 Feb 28. PubMed
Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine. Nakazawa T, Kikuchi M, Ishikawa M, Yamamori H, Nagayasu K, Matsumoto T, Fujimoto M, Yasuda Y, Fujiwara M, Okada S, Matsumura K, Kasai A, Hayata-Takano A, Shintani N, Numata S, Takuma K, Akamatsu W, Okano H, Nakaya A, Hashimoto H, Hashimoto R. Schizophr Res. 2017 Mar;181:75-82. doi: 10.1016/j.schres.2016.10.012. Epub 2016 Oct 27. PubMed
Bovine trophectoderm cells induced from bovine fibroblasts with induced pluripotent stem cell reprogramming factors. Talbot NC, Sparks WO, Phillips CE, Ealy AD, Powell AM, Caperna TJ, Garrett WM, Donovan DM, Blomberg LA. Mol Reprod Dev. 2017 Jun;84(6):468-485. doi: 10.1002/mrd.22797. Epub 2017 Apr 12. PubMed
Promyelocytic Leukemia Protein Is an Essential Regulator of Stem Cell Pluripotency and Somatic Cell Reprogramming. Hadjimichael C, Chanoumidou K, Nikolaou C, Klonizakis A, Theodosi GI, Makatounakis T, Papamatheakis J, Kretsovali A. Stem Cell Reports. 2017 May 9;8(5):1366-1378. doi: 10.1016/j.stemcr.2017.03.006. Epub 2017 Apr 6. PubMed
Crystal structure of Zen4 in the apo state reveals a missing conformation of kinesin. Guan R, Zhang L, Su QP, Mickolajczyk KJ, Chen GY, Hancock WO, Sun Y, Zhao Y, Chen Z. Nat Commun. 2017 Apr 10;8:14951. doi: 10.1038/ncomms14951. PubMed
Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model. Rivetti di Val Cervo P, Romanov RA, Spigolon G, Masini D, Martin-Montanez E, Toledo EM, La Manno G, Feyder M, Pifl C, Ng YH, Sanchez SP, Linnarsson S, Wernig M, Harkany T, Fisone G, Arenas E. Nat Biotechnol. 2017 May;35(5):444-452. doi: 10.1038/nbt.3835. Epub 2017 Apr 10. PubMed
Deterministic versus stochastic model of reprogramming: new evidence from cellular barcoding technique. Yunusova AM, Fishman VS, Vasiliev GV, Battulin NR. Open Biol. 2017 Apr;7(4). pii: 160311. doi: 10.1098/rsob.160311. PubMed
Glucose Can Epigenetically Alter the Gene Expression of Neurotrophic Factors in the Murine Brain Cells. Hossain MS, Oomura Y, Katafuchi T. Mol Neurobiol. 2017 May 13. doi: 10.1007/s12035-017-0578-3. PubMed
Generation of Induced Pluripotent Stem Cells in Defined Three-Dimensional Hydrogels. Caiazzo M, Tabata Y, Lutolf M. Methods Mol Biol. 2017;1612:65-78. doi: 10.1007/978-1-4939-7021-6_5. PubMed
miR-524-5p of the primate-specific C19MC miRNA cluster targets TP53IPN1- and EMT-associated genes to regulate cellular reprogramming. Nguyen PNN, Choo KB, Huang CJ, Sugii S, Cheong SK, Kamarul T. Stem Cell Res Ther. 2017 Sep 29;8(1):214. doi: 10.1186/s13287-017-0666-3. PubMed
Reprogramming Factors Remodel Melanoma Cell Phenotype by Changing Stat3 Expression. Wang Y, Mou Y, Zhang H, Wang X, Li R, Cheng Z, Liu X. Int J Med Sci. 2017 Nov 2;14(13):1402-1409. doi: 10.7150/ijms.21952. eCollection 2017. PubMed
Reversible dual inhibitor against G9a and DNMT1 improves human iPSC derivation enhancing MET and facilitating transcription factor engagement to the genome. Rodriguez-Madoz JR, San Jose-Eneriz E, Rabal O, Zapata-Linares N, Miranda E, Rodriguez S, Porciuncula A, Vilas-Zornoza A, Garate L, Segura V, Guruceaga E, Agirre X, Oyarzabal J, Prosper F. PLoS One. 2017 Dec 27;12(12):e0190275. doi: 10.1371/journal.pone.0190275. eCollection 2017. PubMed

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