Induction of pluripotent stem cells from adult human fibroblasts by defined factors.
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S
Cell. 2007 Nov 30. 131(5):861-72.
PubMed
Journal
Plasmids from Related Articles
- Induced Pluripotent Stem Cells Generated Without Viral Integration.
Science. 2008 Sep 25. ():.
19767: pAd-Sox2,
19768: pAd-Oct4,
19769: pAd-cMyc T58A,
19770: pAd-Klf4 ...
- Generation of human induced pluripotent stem cells from dermal fibroblasts.
Proc Natl Acad Sci U S A. 2008 Feb 26. 105(8):2883-8.
17964: pMXs-hOCT4 (Plath),
17965: pMXs-hSOX2 (Plath),
17966: pMXs-hcMYC (Plath),
17967: pMXs-hKLF4 (Plath),
18115: pMXs-hNANOG (Plath) ...
- Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells.
Science. 2007 Nov 20. ():.
16350: pGEM-LIN28,
16351: pGEM-Nanog,
16352: pGEM-Oct4,
16353: pGEM-Sox2,
16577: pSin-EF2-Sox2-Pur ...
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined fa...
Cell. 2006 Aug 25. 126(4):663-76.
13351: pMXs-Ecat1,
13352: pMXs-Esg1,
13353: pMXs-Fbx15,
13354: pMXs-Nanog,
13355: pMXs-ERas ...
- Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells.
Cell Stem Cell. 2008 Feb 7. 2(2):151-9.
20322: TetO-FUW-Klf4,
20323: TetO-FUW-oct4,
20324: TetO-FUW-cMYC,
20326: TetO-FUW-sox2 ...
-
Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced...
Stem Cells. 2009 May . 27(5):1042-9.
21627: pKP332 (Lenti-OSK1) ...
- Reprogramming of murine and human somatic cells using a single polycistronic vector.
Proc Natl Acad Sci U S A. 2009 Jan 6. 106(1):157-62.
20321: TetO-FUW-OSKM,
20325: FUW-SOKM,
20327: FUW-SOK,
20328: FUW-OSKM,
20329: FUW-SO ...
- Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse.
Cell Stem Cell. 2008 Mar 6. 2(3):230-40.
19763: pLV-tetO-myc T58A,
19764: pLV-tetO-Klf4,
19765: pLV-tetO-Sox2,
19766: pLV-tetO-Oct4 ...
- Promotion of direct reprogramming by transformation-deficient Myc.
Proc Natl Acad Sci U S A. 2010 Jul 26. ():.
26022: pMXs-Hu-L-Myc,
26023: pMXs-Ms-L-Myc,
26024: pMXs-Ms-c-Myc-W136E ...
- Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors.
Science. 2008 Oct 9. ():.
19771: pCX-OKS-2A,
19772: pCX-cMyc ...
-
Improved Efficiency and Pace of Generating Induced Pluripotent Stem Cells from Human Adult and Fetal...
Stem Cells. 2008 May 29. ():.
18918: tetO7_Ef1a_OCT4,
18919: tetO7_Ef1a_SOX2,
18920: Ef1a_NANOG_Ires_Puro,
18921: Ef1a_LIN28_Ires_Puro,
18922: Ef1a_Large T-antigen_Ires_Puro ...
- A high-efficiency system for the generation and study of human induced pluripotent stem cells.
Cell Stem Cell. 2008 Sep 11. 3(3):340-5.
19775: FU-tet-o-hc-myc,
19776: FU-tet-o-hNanogP8,
19777: FU-tet-o-hKLF4,
19778: FU-tet-o-hOct4,
19779: FU-tet-o-hSox2 ...
-
Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse ...
Mol Cell Biol. 2003 Apr . 23(8):2699-708.
13404: pFbx15(-6/+134)-Luc,
13405: pFbx15(-73/+114)-Luc,
13406: pFbx15(-201/+114)-Luc,
13407: pFbx15(-332/+114)-Luc,
13408: pFbx15(-638/+114)-Luc ...
- Direct conversion of fibroblasts to functional neurons by defined factors.
Nature. 2010 Feb 25. 463(7284):1035-41.
27150: Tet-O-FUW-Ascl1,
27151: Tet-O-FUW-Brn2,
27152: Tet-O-FUW-Myt1l,
30129: Tet-O-FUW-Neurod1,
30130: Tet-O-FUW-EGFP ...
- A drug-inducible system for direct reprogramming of human somatic cells to pluripotency.
Cell Stem Cell. 2008 Sep 11. 3(3):346-53.
20342: FUW-M2rtTA,
20723: FUW-tetO-hMYC,
20724: FUW-tetO-hSOX2,
20725: FUW-tetO-hKLF4,
20726: FUW-tetO-hOCT4 ...
- Suppression of induced pluripotent stem cell generation by the p53-p21 pathway.
Nature. 2009 Aug 27. 460(7259):1132-5.
22724: pMXs-DsRed Express,
22725: pMXs-p53,
22726: pMXs-p53P275S,
22727: pMXs-p53D278N,
22728: pMXs-p53S58A ...
-
Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ...
Proc Natl Acad Sci U S A. 2010 May 18. 107(20):9222-7.
26274: pBRPyCAG-fmKlf4-DsRed-Ip,
26277: pBRPyCAG-hKlf2-DsRed-Ip,
26279: pGL2-hOct4 DE-SV40-Luc,
26280: pGL2- Empty control -SV40-Luc ...
- Generation of mouse-induced pluripotent stem cells with plasmid vectors.
Nat Protoc. 2010 . 5(3):418-28.
- Virus-free induction of pluripotency and subsequent excision of reprogramming factors.
Nature. 2009 Mar 1. ():.
20865: pCAGMKOSiE,
20866: pCAG2LMKOSimO ...
-
Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient hum...
Proc Natl Acad Sci U S A. 2009 Aug 4. 106(31):12759-64.
22240: pLM-vexGFP-Oct4,
23242: pLM-mCitrine-Sox2,
23243: pLM-mCherry-Klf4,
23244: pLM-mCerulean-cMyc ...
- Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency.
Nat Methods. 2009 May . 6(5):370-6.
21312: PL-SIN-PGK-EiP,
21313: PL-SIN-EOS-C(3+)-EiP,
21314: PL-SIN-EOS-S(4+)-EiP,
21315: pMXs-mRFP1,
21316: PL-SIN-PGK-EGFP ...
- Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes.
Nat Biotechnol. 2008 Nov . 26(11):1276-84.
20072: pMSCV-Flag-hOct4,
20073: pMSCV-Flag-hSox2,
20074: pMSCV-Flag-hKlf4,
20075: pMSCV-Flag-cMyc T58A,
20076: pMSCVpuro-Flag-cMyc T58A ...
- piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells.
Nature. 2009 Mar 1. ():.
- Reprogramming of human somatic cells to pluripotency with defined factors.
Nature. 2007 Dec 23. ():.
17225: pMIG-hOCT4,
17226: pMIG-hSOX2,
17227: pMIG-hKLF4 ...
- Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
Science. 2009 Mar 26.
20922: pEP4 E02S EN2L,
20923: pEP4 E02S EM2K,
20924: pEP4 E02S CK2M EN2L,
20925: pEP4 E02S EN2K,
20926: pCEP4-M2L ...
- Chd1 regulates open chromatin and pluripotency of embryonic stem cells.
Nature. 2009 Jul 8. ():.
21904: pSicoR-mCh-Chd1i1,
21905: pSicoR-mCh-GFPi,
21906: pSicoR-mCh-Oct4i,
21907: pSicoR-mCh-empty,
21908: pSicoR-mCh-Chd1i4 ...
- Generation of germline-competent induced pluripotent stem cells.
Nature. 2007 Jun 6. ():.
