pSMPP Citations (5)
Originally described in: A Method for the Acute and Rapid Degradation of Endogenous Proteins.Clift D, McEwan WA, Labzin LI, Konieczny V, Mogessie B, James LC, Schuh M Cell. 2017 Nov 13. pii: S0092-8674(17)31255-2. doi: 10.1016/j.cell.2017.10.033. PubMed Journal
Articles Citing pSMPP
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Cholesterol determines the cytosolic entry and seeded aggregation of tau.
Tuck BJ, Miller LVC, Katsinelos T, Smith AE, Wilson EL, Keeling S, Cheng S, Vaysburd MJ, Knox C, Tredgett L, Metzakopian E, James LC, McEwan WA.
Cell Rep. 2022 May 3;39(5):110776. doi: 10.1016/j.celrep.2022.110776.
PubMed
Associated Plasmids |
| Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates. Kiss L, Rhinesmith T, Luptak J, Dickson CF, Weidenhausen J, Smyly S, Yang JC, Maslen SL, Sinning I, Neuhaus D, Clift D, James LC. Nat Commun. 2023 Apr 15;14(1):2160. doi: 10.1038/s41467-023-37504-x. PubMed |
| Super-resolution imaging unveils the self-replication of tau aggregates upon seeding. Dimou E, Katsinelos T, Meisl G, Tuck BJ, Keeling S, Smith AE, Hidari E, Lam JYL, Burke M, Lovestam S, Ranasinghe RT, McEwan WA, Klenerman D. Cell Rep. 2023 Jul 25;42(7):112725. doi: 10.1016/j.celrep.2023.112725. Epub 2023 Jul 1. PubMed |
| SREBP2 regulates the endothelial response to cytokines via direct transcriptional activation of KLF6. Fowler JWM, Boutagy NE, Zhang R, Horikami D, Whalen MB, Romanoski CE, Sessa WC. J Lipid Res. 2023 Aug;64(8):100411. doi: 10.1016/j.jlr.2023.100411. Epub 2023 Jul 10. PubMed |
| Sensitive detection and propagation of brain-derived tau assemblies in HEK293-based wild-type tau seeding assays. Huang M, McEwan WA. J Biol Chem. 2025 Mar;301(3):108245. doi: 10.1016/j.jbc.2025.108245. Epub 2025 Jan 27. PubMed |
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