lenti-sgRNA hygro Citations (18)
Originally described in: A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma.Stringer BW, Day BW, D'Souza RCJ, Jamieson PR, Ensbey KS, Bruce ZC, Lim YC, Goasdoue K, Offenhauser C, Akgul S, Allan S, Robertson T, Lucas P, Tollesson G, Campbell S, Winter C, Do H, Dobrovic A, Inglis PL, Jeffree RL, Johns TG, Boyd AW Sci Rep. 2019 Mar 20;9(1):4902. doi: 10.1038/s41598-019-41277-z. PubMed Journal
Articles Citing lenti-sgRNA hygro
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| Cas9(+) conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond. Roberts AW, Popov LM, Mitchell G, Ching KL, Licht DJ, Golovkine G, Barton GM, Cox JS. Elife. 2019 Jun 17;8. pii: 45957. doi: 10.7554/eLife.45957. PubMed |
| Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD. Hewitt G, Borel V, Segura-Bayona S, Takaki T, Ruis P, Bellelli R, Lehmann LC, Sommerova L, Vancevska A, Tomas-Loba A, Zhu K, Cooper C, Fugger K, Patel H, Goldstone R, Schneider-Luftman D, Herbert E, Stamp G, Brough R, Pettitt S, Lord CJ, West SC, Ahel I, Ahel D, Chapman JR, Deindl S, Boulton SJ. Mol Cell. 2021 Feb 18;81(4):767-783.e11. doi: 10.1016/j.molcel.2020.12.006. Epub 2020 Dec 16. PubMed |
| METTL16 exerts an m(6)A-independent function to facilitate translation and tumorigenesis. Su R, Dong L, Li Y, Gao M, He PC, Liu W, Wei J, Zhao Z, Gao L, Han L, Deng X, Li C, Prince E, Tan B, Qing Y, Qin X, Shen C, Xue M, Zhou K, Chen Z, Xue J, Li W, Qin H, Wu X, Sun M, Nam Y, Chen CW, Huang W, Horne D, Rosen ST, He C, Chen J. Nat Cell Biol. 2022 Feb;24(2):205-216. doi: 10.1038/s41556-021-00835-2. Epub 2022 Feb 10. PubMed |
| RB1 loss overrides PARP inhibitor sensitivity driven by RNASEH2B loss in prostate cancer. Miao C, Tsujino T, Takai T, Gui F, Tsutsumi T, Sztupinszki Z, Wang Z, Azuma H, Szallasi Z, Mouw KW, Zou L, Kibel AS, Jia L. Sci Adv. 2022 Feb 18;8(7):eabl9794. doi: 10.1126/sciadv.abl9794. Epub 2022 Feb 18. PubMed |
| METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism. Han L, Dong L, Leung K, Zhao Z, Li Y, Gao L, Chen Z, Xue J, Qing Y, Li W, Pokharel SP, Gao M, Chen M, Shen C, Tan B, Small A, Wang K, Zhang Z, Qin X, Yang L, Wunderlich M, Zhang B, Mulloy JC, Marcucci G, Chen CW, Wei M, Su R, Chen J, Deng X. Cell Stem Cell. 2023 Jan 5;30(1):52-68.e13. doi: 10.1016/j.stem.2022.12.006. PubMed |
| Stellettin B Induces Cell Death in Bladder Cancer Via Activating the Autophagy/DAPK2/Apoptosis Signaling Cascade. Chang CH, Lin BJ, Chen CH, Nguyen NL, Hsieh TH, Su JH, Chen MC. Mar Drugs. 2023 Jan 21;21(2):73. doi: 10.3390/md21020073. PubMed |
| QKI shuttles internal m(7)G-modified transcripts into stress granules and modulates mRNA metabolism. Zhao Z, Qing Y, Dong L, Han L, Wu D, Li Y, Li W, Xue J, Zhou K, Sun M, Tan B, Chen Z, Shen C, Gao L, Small A, Wang K, Leung K, Zhang Z, Qin X, Deng X, Xia Q, Su R, Chen J. Cell. 2023 Jul 20;186(15):3208-3226.e27. doi: 10.1016/j.cell.2023.05.047. Epub 2023 Jun 27. PubMed |
| METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation. Xue M, Dong L, Zhang H, Li Y, Qiu K, Zhao Z, Gao M, Han L, Chan AKN, Li W, Leung K, Wang K, Pokharel SP, Qing Y, Liu W, Wang X, Ren L, Bi H, Yang L, Shen C, Chen Z, Melstrom L, Li H, Timchenko N, Deng X, Huang W, Rosen ST, Tian J, Xu L, Diao J, Chen CW, Chen J, Shen B, Chen H, Su R. J Hematol Oncol. 2024 Feb 1;17(1):7. doi: 10.1186/s13045-024-01526-9. PubMed |
| The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma. Malone CF, Mabe NW, Forman AB, Alexe G, Engel KL, Chen YC, Soeung M, Salhotra S, Basanthakumar A, Liu B, Dent SYR, Stegmaier K. Sci Adv. 2024 May 31;10(22):eadm9449. doi: 10.1126/sciadv.adm9449. Epub 2024 May 31. PubMed |
| History of tuberculosis disease is associated with genetic regulatory variation in Peruvians. Nieto-Caballero VE, Reijneveld JF, Ruvalcaba A, Innocenzi G, Abeydeera N, Asgari S, Lopez K, Iwany SK, Luo Y, Nathan A, Fernandez-Salinas D, Chinas M, Huang CC, Zhang Z, Leon SR, Calderon RI, Lecca L, Budzik JM, Murray M, Van Rhijn I, Raychaudhuri S, Moody DB, Suliman S, Gutierrez-Arcelus M. PLoS Genet. 2024 Jun 13;20(6):e1011313. doi: 10.1371/journal.pgen.1011313. eCollection 2024 Jun. PubMed |
| TBK1 and IKKepsilon protect target cells from IFNgamma-mediated T cell killing via an inflammatory apoptotic mechanism. Sun ND, Carr AR, Krogman EN, Chawla Y, Zhong J, Guttormson MC, Chan M, Hsu MA, Dong H, Bogunovic D, Pandey A, Rogers LM, Ting AT. bioRxiv [Preprint]. 2024 Aug 8:2024.08.06.606693. doi: 10.1101/2024.08.06.606693. PubMed |
| The role of gene duplication and paralog specialisation in the evolution of the mammalian PRPS complex. Karki BR, MacMillan AC, Vicente-Munoz S, Greis KD, Romick LE, Cunningham JT. Nat Commun. 2025 Jul 8;16(1):6076. doi: 10.1038/s41467-025-61216-z. PubMed |
A side-by-side comparison of variant function measurements using deep mutational scanning and base editing.
Sokirniy I, Inam H, Tomaszkiewicz M, Reynolds J, McCandlish D, Pritchard J.
Nucleic Acids Res. 2025 Jul 19;53(14):gkaf738. doi: 10.1093/nar/gkaf738.
PubMed
Associated Plasmids |
| ALKBH1 Drives Tumorigenesis and Drug Resistance via tRNA-decoding Reprogramming and Codon-biased Translation. Shen C, Che Y, Zhou K, Wang K, Li W, Xue D, Wu T, Yang L, Chen M, Sheng Y, Zhang C, Robinson S, Chen H, Sau L, Chen Z, Wunderlich M, Han L, Tang T, Qing Y, Wu D, Sun M, Leung K, Dabrowska K, Pirrotte P, Hu YC, Ghoda LY, Zhang B, Mulloy JC, Wei M, Marcucci G, He C, Deng X, Chen J. Cancer Discov. 2025 Nov 3;15(11):2298-2325. doi: 10.1158/2159-8290.CD-24-1043. PubMed |
| PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer. Young AA, Juhler IG, Pierce JR, Bohlin HE, Harper HA, Onishile DS, Chua RN, Liu ME, Gardner EN, Elzey BD, Cottrell KA. RNA. 2025 Oct 16;31(11):1599-1618. doi: 10.1261/rna.080637.125. PubMed |
| ZYS-1 is not an ADAR1 inhibitor. Smoak CN, Gardner EN, Chua RN, Cottrell KA. RNA. 2025 Nov 17;31(12):1703-1711. doi: 10.1261/rna.080721.125. PubMed |
| EXO1 as a therapeutic target for Fanconi Anaemia, ZRSR2 and BRCA1-A complex deficient cancers. Maric M, Segura-Bayona S, Kuthethur R, Takaki T, Borel V, Stanage TH, Ivanov MP, Parnandi N, Hewitt G, Millar R, Fonseca CS, Patel H, Llorian M, Warchal S, Howell M, Chaudhuri AR, Kotsantis P, Boulton SJ. Nat Commun. 2025 Sep 26;16(1):8476. doi: 10.1038/s41467-025-63349-7. PubMed |
| Genome-wide screen in Mycobacterium tuberculosis infected macrophages reveals innate regulation of antibacterial mediators by IRF2. Roberts AW, Del Cid LN, Garelis NE, Cox JS. bioRxiv [Preprint]. 2025 Sep 29:2025.09.26.678671. doi: 10.1101/2025.09.26.678671. PubMed |
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