lenti_dCas9-KRAB-MeCP2 Citations (19)

Originally described in: Interrogation of genome-wide, experimentally dissected gene regulatory networks reveals mechanisms underlying dynamic cellular state control
Tan X, Worley J, Turunen M, Wong K, Fernández EC, Paull E, Jones S, Wang J, Noh H, Salvatori B, Chavez A, Califano A bioRxiv 2021.06.28.449297 Journal

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Articles Citing lenti_dCas9-KRAB-MeCP2

Articles
Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology. Zhang N, Mendieta-Esteban J, Magli A, Lilja KC, Perlingeiro RCR, Marti-Renom MA, Tsirigos A, Dynlacht BD. Nat Commun. 2020 Dec 4;11(1):6222. doi: 10.1038/s41467-020-19999-w. PubMed
KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress. Moonen JR, Chappell J, Shi M, Shinohara T, Li D, Mumbach MR, Zhang F, Nair RV, Nasser J, Mai DH, Taylor S, Wang L, Metzger RJ, Chang HY, Engreitz JM, Snyder MP, Rabinovitch M. Nat Commun. 2022 Aug 23;13(1):4941. doi: 10.1038/s41467-022-32566-9. PubMed
Subtype-specific 3D genome alteration in acute myeloid leukaemia. Xu J, Song F, Lyu H, Kobayashi M, Zhang B, Zhao Z, Hou Y, Wang X, Luan Y, Jia B, Stasiak L, Wong JH, Wang Q, Jin Q, Jin Q, Fu Y, Yang H, Hardison RC, Dovat S, Platanias LC, Diao Y, Yang Y, Yamada T, Viny AD, Levine RL, Claxton D, Broach JR, Zheng H, Yue F. Nature. 2022 Nov;611(7935):387-398. doi: 10.1038/s41586-022-05365-x. Epub 2022 Oct 26. PubMed
Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection. King CR, Liu Y, Amato KA, Schaack GA, Hu T, Smith JA, Mehle A. bioRxiv. 2023 Feb 7:2023.02.07.527556. doi: 10.1101/2023.02.07.527556. Preprint. PubMed
Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury. Kwon A, Lee NY, Yu JH, Choi MG, Park J, Koo JH. Cell Death Dis. 2024 Jan 15;15(1):51. doi: 10.1038/s41419-024-06448-5. PubMed
SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion. Leuzzi G, Vasciaveo A, Taglialatela A, Chen X, Firestone TM, Hickman AR, Mao W, Thakar T, Vaitsiankova A, Huang JW, Cuella-Martin R, Hayward SB, Kesner JS, Ghasemzadeh A, Nambiar TS, Ho P, Rialdi A, Hebrard M, Li Y, Gao J, Gopinath S, Adeleke OA, Venters BJ, Drake CG, Baer R, Izar B, Guccione E, Keogh MC, Guerois R, Sun L, Lu C, Califano A, Ciccia A. Cell. 2024 Feb 15;187(4):861-881.e32. doi: 10.1016/j.cell.2024.01.008. Epub 2024 Jan 31. PubMed
Detecting subtle transcriptomic perturbations induced by lncRNAs knock-down in single-cell CRISPRi screening using a new sparse supervised autoencoder neural network. Truchi M, Lacoux C, Gille C, Fassy J, Magnone V, Lopes Goncalves R, Girard-Riboulleau C, Manosalva-Pena I, Gautier-Isola M, Lebrigand K, Barbry P, Spicuglia S, Vassaux G, Rezzonico R, Barlaud M, Mari B. Front Bioinform. 2024 Mar 4;4:1340339. doi: 10.3389/fbinf.2024.1340339. eCollection 2024. PubMed
Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease. Linna-Kuosmanen S, Schmauch E, Galani K, Ojanen J, Boix CA, Ord T, Toropainen A, Singha PK, Moreau PR, Harju K, Blazeski A, Segerstolpe A, Lahtinen V, Hou L, Kang K, Meibalan E, Agudelo LZ, Kokki H, Halonen J, Jalkanen J, Gunn J, MacRae CA, Hollmen M, Hartikainen JEK, Kaikkonen MU, Garcia-Cardena G, Tavi P, Kiviniemi T, Kellis M. Cell Rep Med. 2024 May 21;5(5):101556. doi: 10.1016/j.xcrm.2024.101556. PubMed
The Role of IRF9 Upregulation in Modulating Sensitivity to Olaparib and Platinum-Based Chemotherapies in Breast Cancer. Choi S, Bae HG, Jo DG, Kim WY. Genes (Basel). 2024 Jul 22;15(7):959. doi: 10.3390/genes15070959. PubMed
Productive mRNA Chromatin Escape is Promoted by PRMT5 Methylation of SNRPB. DeAngelo JD, Maron MI, Roth JS, Silverstein AM, Gupta V, Stransky S, Basken J, Azofeifa J, Sidoli S, Gamble MJ, Shechter D. bioRxiv [Preprint]. 2024 Aug 12:2024.08.09.607355. doi: 10.1101/2024.08.09.607355. PubMed
The therapeutic implications of all-in-one AAV-delivered epigenome-editing platform in neurodegenerative disorders. Kantor B, O'Donovan B, Rittiner J, Hodgson D, Lindner N, Guerrero S, Dong W, Zhang A, Chiba-Falek O. Nat Commun. 2024 Aug 23;15(1):7259. doi: 10.1038/s41467-024-50515-6. PubMed
Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization. Wang C, Leong MM, Ding W, Narita Y, Liu X, Wang H, Yiu SPT, Lee J, Zhao KRS, Cui A, Gewurz B, Hammerschmidt W, Teng M, Zhao B. EMBO Rep. 2025 Feb;26(3):810-835. doi: 10.1038/s44319-024-00357-6. Epub 2025 Jan 2. PubMed
CHD7 binds to insulators during neuronal differentiation. Qiu J, Jadali A, Martinez E, Song Z, Ni JZ, Kwan KY. bioRxiv [Preprint]. 2025 Mar 29:2025.03.28.646031. doi: 10.1101/2025.03.28.646031. PubMed
A distal enhancer with ETV4 binding is critical for UCP1 expression and thermogenesis in brown fat. Xue P, Holloway N, Tran A, Lin F, Dinh J, Yang C, Wang Y, Yi D, Sul HS. Genes Dev. 2025 Jul 1;39(13-14):808-825. doi: 10.1101/gad.352748.125. PubMed
Landscape of the Epstein-Barr virus-host chromatin interactome and gene regulation. Tian SZ, Yang Y, Ning D, Yu T, Gao T, Deng Y, Fang K, Xu Y, Jing K, Huang G, Chen G, Yin P, Li Y, Zeng F, Tian R, Zheng M. EMBO J. 2025 Jul;44(13):3872-3915. doi: 10.1038/s44318-025-00466-5. Epub 2025 May 27. PubMed
PRMT5 activity sustains histone production to maintain genome integrity. Roth JS, DeAngelo JD, Young DL, Maron MI, Saha A, Pinto H, Gupta V, Jacobs N, Hegde S, Aguilan JT, Basken J, Azofeifa J, Query CC, Sidoli S, Skoultchi AI, Shechter D. bioRxiv [Preprint]. 2025 Jul 7:2025.07.03.663002. doi: 10.1101/2025.07.03.663002. PubMed
Genome-wide mapping of EBV-induced genomic variations identifies the role of MUC19 in EBV latency. Yu J, Wang Y, Liu Q, Zhou X, Robertson ES, Pei Y. mBio. 2025 Nov 12;16(11):e0205525. doi: 10.1128/mbio.02055-25. Epub 2025 Sep 25. PubMed
Productive mRNA chromatin escape is promoted by PRMT5 activity. DeAngelo JD, Maron MI, Roth JS, Hegde S, Silverstein AM, Gupta V, Stransky S, Basken J, Azofeifa J, Query CC, Sidoli S, Gamble MJ, Shechter D. Mol Cell. 2025 Nov 6;85(21):4016-4031.e9. doi: 10.1016/j.molcel.2025.09.021. Epub 2025 Oct 13. PubMed
YAP/TAZ-VGLL3 governs adipocyte fate via epigenetic reprogramming of PPARgamma and its target enhancers. Seol T, Kang JG, Ryu K, Kim W, Hwang D, Cho S, Song D, Ku B, Tran YTH, Jeong SH, Cho WK, Lim DS. Sci Adv. 2026 Jan 16;12(3):eaea7235. doi: 10.1126/sciadv.aea7235. Epub 2026 Jan 14. PubMed

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