lenti_dCas9-KRAB-MeCP2 Citations (12)
Originally described in: Interrogation of genome-wide, experimentally dissected gene regulatory networks reveals mechanisms underlying dynamic cellular state controlTan X, Worley J, Turunen M, Wong K, Fernández EC, Paull E, Jones S, Wang J, Noh H, Salvatori B, Chavez A, Califano A bioRxiv 2021.06.28.449297 Journal
Articles Citing lenti_dCas9-KRAB-MeCP2
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Muscle progenitor specification and myogenic differentiation are associated with changes in chromatin topology. Zhang N, Mendieta-Esteban J, Magli A, Lilja KC, Perlingeiro RCR, Marti-Renom MA, Tsirigos A, Dynlacht BD. Nat Commun. 2020 Dec 4;11(1):6222. doi: 10.1038/s41467-020-19999-w. PubMed |
KLF4 recruits SWI/SNF to increase chromatin accessibility and reprogram the endothelial enhancer landscape under laminar shear stress. Moonen JR, Chappell J, Shi M, Shinohara T, Li D, Mumbach MR, Zhang F, Nair RV, Nasser J, Mai DH, Taylor S, Wang L, Metzger RJ, Chang HY, Engreitz JM, Snyder MP, Rabinovitch M. Nat Commun. 2022 Aug 23;13(1):4941. doi: 10.1038/s41467-022-32566-9. PubMed |
Subtype-specific 3D genome alteration in acute myeloid leukaemia. Xu J, Song F, Lyu H, Kobayashi M, Zhang B, Zhao Z, Hou Y, Wang X, Luan Y, Jia B, Stasiak L, Wong JH, Wang Q, Jin Q, Jin Q, Fu Y, Yang H, Hardison RC, Dovat S, Platanias LC, Diao Y, Yang Y, Yamada T, Viny AD, Levine RL, Claxton D, Broach JR, Zheng H, Yue F. Nature. 2022 Nov;611(7935):387-398. doi: 10.1038/s41586-022-05365-x. Epub 2022 Oct 26. PubMed |
Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection. King CR, Liu Y, Amato KA, Schaack GA, Hu T, Smith JA, Mehle A. bioRxiv. 2023 Feb 7:2023.02.07.527556. doi: 10.1101/2023.02.07.527556. Preprint. PubMed |
Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury. Kwon A, Lee NY, Yu JH, Choi MG, Park J, Koo JH. Cell Death Dis. 2024 Jan 15;15(1):51. doi: 10.1038/s41419-024-06448-5. PubMed |
SMARCAL1 is a dual regulator of innate immune signaling and PD-L1 expression that promotes tumor immune evasion. Leuzzi G, Vasciaveo A, Taglialatela A, Chen X, Firestone TM, Hickman AR, Mao W, Thakar T, Vaitsiankova A, Huang JW, Cuella-Martin R, Hayward SB, Kesner JS, Ghasemzadeh A, Nambiar TS, Ho P, Rialdi A, Hebrard M, Li Y, Gao J, Gopinath S, Adeleke OA, Venters BJ, Drake CG, Baer R, Izar B, Guccione E, Keogh MC, Guerois R, Sun L, Lu C, Califano A, Ciccia A. Cell. 2024 Feb 15;187(4):861-881.e32. doi: 10.1016/j.cell.2024.01.008. Epub 2024 Jan 31. PubMed |
Detecting subtle transcriptomic perturbations induced by lncRNAs knock-down in single-cell CRISPRi screening using a new sparse supervised autoencoder neural network. Truchi M, Lacoux C, Gille C, Fassy J, Magnone V, Lopes Goncalves R, Girard-Riboulleau C, Manosalva-Pena I, Gautier-Isola M, Lebrigand K, Barbry P, Spicuglia S, Vassaux G, Rezzonico R, Barlaud M, Mari B. Front Bioinform. 2024 Mar 4;4:1340339. doi: 10.3389/fbinf.2024.1340339. eCollection 2024. PubMed |
Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease. Linna-Kuosmanen S, Schmauch E, Galani K, Ojanen J, Boix CA, Ord T, Toropainen A, Singha PK, Moreau PR, Harju K, Blazeski A, Segerstolpe A, Lahtinen V, Hou L, Kang K, Meibalan E, Agudelo LZ, Kokki H, Halonen J, Jalkanen J, Gunn J, MacRae CA, Hollmen M, Hartikainen JEK, Kaikkonen MU, Garcia-Cardena G, Tavi P, Kiviniemi T, Kellis M. Cell Rep Med. 2024 May 21;5(5):101556. doi: 10.1016/j.xcrm.2024.101556. PubMed |
The Role of IRF9 Upregulation in Modulating Sensitivity to Olaparib and Platinum-Based Chemotherapies in Breast Cancer. Choi S, Bae HG, Jo DG, Kim WY. Genes (Basel). 2024 Jul 22;15(7):959. doi: 10.3390/genes15070959. PubMed |
Productive mRNA Chromatin Escape is Promoted by PRMT5 Methylation of SNRPB. DeAngelo JD, Maron MI, Roth JS, Silverstein AM, Gupta V, Stransky S, Basken J, Azofeifa J, Sidoli S, Gamble MJ, Shechter D. bioRxiv [Preprint]. 2024 Aug 12:2024.08.09.607355. doi: 10.1101/2024.08.09.607355. PubMed |
The therapeutic implications of all-in-one AAV-delivered epigenome-editing platform in neurodegenerative disorders. Kantor B, O'Donovan B, Rittiner J, Hodgson D, Lindner N, Guerrero S, Dong W, Zhang A, Chiba-Falek O. Nat Commun. 2024 Aug 23;15(1):7259. doi: 10.1038/s41467-024-50515-6. PubMed |
Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization. Wang C, Leong MM, Ding W, Narita Y, Liu X, Wang H, Yiu SPT, Lee J, Zhao KRS, Cui A, Gewurz B, Hammerschmidt W, Teng M, Zhao B. EMBO Rep. 2025 Feb;26(3):810-835. doi: 10.1038/s44319-024-00357-6. Epub 2025 Jan 2. PubMed |
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