pBA950 Citations (4)
Originally described in: Combinatorial single-cell CRISPR screens by direct guide RNA capture and targeted sequencing.Replogle JM, Norman TM, Xu A, Hussmann JA, Chen J, Cogan JZ, Meer EJ, Terry JM, Riordan DP, Srinivas N, Fiddes IT, Arthur JG, Alvarado LJ, Pfeiffer KA, Mikkelsen TS, Weissman JS, Adamson B Nat Biotechnol. 2020 Aug;38(8):954-961. doi: 10.1038/s41587-020-0470-y. Epub 2020 Mar 30. PubMed Journal
Articles Citing pBA950
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Maximizing CRISPRi efficacy and accessibility with dual-sgRNA libraries and optimal effectors.
Replogle JM, Bonnar JL, Pogson AN, Liem CR, Maier NK, Ding Y, Russell BJ, Wang X, Leng K, Guna A, Norman TM, Pak RA, Ramos DM, Ward ME, Gilbert LA, Kampmann M, Weissman JS, Jost M.
eLife. 2022 Dec 28;11:e81856. doi: 10.7554/eLife.81856.
PubMed
Associated Plasmids |
| A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function. Saunders RA, Allen WE, Pan X, Sandhu J, Lu J, Lau TK, Smolyar K, Sullivan ZA, Dulac C, Weissman JS, Zhuang X. bioRxiv [Preprint]. 2025 Feb 17:2024.11.18.624217. doi: 10.1101/2024.11.18.624217. PubMed |
Multiome Perturb-seq unlocks scalable discovery of integrated perturbation effects on the transcriptome and epigenome.
Metzner E, Southard KM, Norman TM.
Cell Syst. 2025 Jan 15;16(1):101161. doi: 10.1016/j.cels.2024.12.002. Epub 2024 Dec 16.
PubMed
Associated Plasmids |
| Perturb-Multimodal: A platform for pooled genetic screens with imaging and sequencing in intact mammalian tissue. Saunders RA, Allen WE, Pan X, Sandhu J, Lu J, Lau TK, Smolyar K, Sullivan ZA, Dulac C, Weissman JS, Zhuang X. Cell. 2025 Aug 21;188(17):4790-4809.e22. doi: 10.1016/j.cell.2025.05.022. Epub 2025 Jun 12. PubMed |
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