pMK1334 Citations (9)
Originally described in: CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons.Tian R, Gachechiladze MA, Ludwig CH, Laurie MT, Hong JY, Nathaniel D, Prabhu AV, Fernandopulle MS, Patel R, Abshari M, Ward ME, Kampmann M Neuron. 2019 Aug 5. pii: S0896-6273(19)30640-3. doi: 10.1016/j.neuron.2019.07.014. PubMed Journal
Articles Citing pMK1334
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| Neuronal enhancers are hotspots for DNA single-strand break repair. Wu W, Hill SE, Nathan WJ, Paiano J, Callen E, Wang D, Shinoda K, van Wietmarschen N, Colon-Mercado JM, Zong D, De Pace R, Shih HY, Coon S, Parsadanian M, Pavani R, Hanzlikova H, Park S, Jung SK, McHugh PJ, Canela A, Chen C, Casellas R, Caldecott KW, Ward ME, Nussenzweig A. Nature. 2021 May;593(7859):440-444. doi: 10.1038/s41586-021-03468-5. Epub 2021 Mar 25. PubMed |
| Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function. Carling PJ, Ryan BJ, McGuinness W, Kataria S, Humble SW, Milde S, Duce JA, Kapadia N, Zuercher WJ, Davis JB, Di Daniel E, Wade-Martins R. Autophagy. 2023 Feb;19(2):692-705. doi: 10.1080/15548627.2022.2095834. Epub 2022 Jul 25. PubMed |
| Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin. Kim H, Leng K, Park J, Sorets AG, Kim S, Shostak A, Embalabala RJ, Mlouk K, Katdare KA, Rose IVL, Sturgeon SM, Neal EH, Ao Y, Wang S, Sofroniew MV, Brunger JM, McMahon DG, Schrag MS, Kampmann M, Lippmann ES. Nat Commun. 2022 Nov 2;13(1):6581. doi: 10.1038/s41467-022-34412-4. PubMed |
| CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis. Samelson AJ, Ariqat N, McKetney J, Rohanitazangi G, Parra Bravo C, Goodness D, Tian R, Grosjean P, Abskharon R, Eisenberg D, Kanaan NM, Gan L, Condello C, Swaney DL, Kampmann M. bioRxiv. 2023 Jun 26:2023.06.16.545386. doi: 10.1101/2023.06.16.545386. Preprint. PubMed |
| Scalable, cell type-selective, AAV-based in vivo CRISPR screening in the mouse brain. Ramani B, Rose IVL, Pan A, Tian R, Ma K, Palop JJ, Kampmann M. bioRxiv [Preprint]. 2023 Jun 27:2023.06.13.544831. doi: 10.1101/2023.06.13.544831. PubMed |
Stress response silencing by an E3 ligase mutated in neurodegeneration.
Haakonsen DL, Heider M, Ingersoll AJ, Vodehnal K, Witus SR, Uenaka T, Wernig M, Rape M.
Nature. 2024 Feb;626(8000):874-880. doi: 10.1038/s41586-023-06985-7. Epub 2024 Jan 31.
PubMed
Associated Plasmids |
| Human iPSC 4R tauopathy model uncovers modifiers of tau propagation. Parra Bravo C, Giani AM, Madero-Perez J, Zhao Z, Wan Y, Samelson AJ, Wong MY, Evangelisti A, Cordes E, Fan L, Ye P, Zhu D, Pozner T, Mercedes M, Patel T, Yarahmady A, Carling GK, Sterky FH, Lee VMY, Lee EB, DeTure M, Dickson DW, Sharma M, Mok SA, Luo W, Zhao M, Kampmann M, Gong S, Gan L. Cell. 2024 May 9;187(10):2446-2464.e22. doi: 10.1016/j.cell.2024.03.015. Epub 2024 Apr 5. PubMed |
| Ciliary biology intersects autism and congenital heart disease. Teerikorpi N, Lasser MC, Wang S, Kostyanovskaya E, Bader E, Sun N, Dea J, Nowakowski TJ, Willsey AJ, Willsey HR. bioRxiv [Preprint]. 2024 Jul 31:2024.07.30.602578. doi: 10.1101/2024.07.30.602578. PubMed |
| CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions. Li E, Benitez C, Boggess SC, Koontz M, Rose IVL, Martinez D, Drager N, Teter OM, Samelson AJ, Pierce N, Ullian EM, Kampmann M. Neuron. 2025 Mar 5;113(5):701-718.e8. doi: 10.1016/j.neuron.2024.12.016. Epub 2025 Jan 14. PubMed |
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