epiCRISPR Citations (12)

Originally described in: An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells.
Xie Y, Wang D, Lan F, Wei G, Ni T, Chai R, Liu D, Hu S, Li M, Li D, Wang H, Wang Y Sci Rep. 2017 May 24;7(1):2320. doi: 10.1038/s41598-017-02456-y. PubMed Journal

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Articles Citing epiCRISPR

Articles
CRISPR/Cas9 mediated establishment of a human CSRP3 compound heterozygous knockout hESC line to model cardiomyopathy and heart failure. Sun L, Li J, Li E, Niu S, Qin Z, Zhi Q, Zhao J, Xiong H, Li Y, Jian L, Zhang L. Stem Cell Res. 2020 Dec;49:102077. doi: 10.1016/j.scr.2020.102077. Epub 2020 Nov 4. PubMed
Establishment of a human MYH6 compound heterozygous knockout hESC line to model cardiomyopathy and congenital heart defects by CRISPR/Cas9 system. Hao E, Zhang G, Mu L, Ma N, Wang T. Stem Cell Res. 2020 Dec 16;50:102128. doi: 10.1016/j.scr.2020.102128. PubMed
Establishment of a KCNQ1 homozygous knockout human embryonic stem cell line by episomal vector-based CRISPR/Cas9 system. Liu X, Zhang S, Chang Y, Wu F, Bai R. Stem Cell Res. 2021 Aug;55:102467. doi: 10.1016/j.scr.2021.102467. Epub 2021 Jul 22. PubMed
A CRISPR/Cas9 strategy for the generation of a FLNC knockout hESC line (WAe009-A-70) to model dilated cardiomyopathy and arrhythmogenic right ventricular cardiomyopathy. Qin Z, Sun L, Sun X, Su H, Gao X. Stem Cell Res. 2021 Oct;56:102562. doi: 10.1016/j.scr.2021.102562. Epub 2021 Oct 7. PubMed
Generation of a TRPM8 knockout hESC line (WAe009-A-A) derived from H9 using CRISPR/Cas9. Bai J, Zhang J, Fu W, Li S, Tian X, Li X, Zhao X, Dong J. Stem Cell Res. 2023 Mar;67:103040. doi: 10.1016/j.scr.2023.103040. Epub 2023 Feb 6. PubMed
Generation of a FLNA knockout hESC line (WAe009-A-P) to model cardiac valvular dysplasia using CRISPR/Cas9. Lu F, Gao Y, Li E. Stem Cell Res. 2023 Jul 1;71:103162. doi: 10.1016/j.scr.2023.103162. PubMed
Generation of a TAB2 knockout hESC line (WAe009-A-Z) derived from H9 using CRISPR/Cas9. Sun W, Li X, Dong J, Zhou Y. Stem Cell Res. 2024 Feb;74:103284. doi: 10.1016/j.scr.2023.103284. Epub 2023 Dec 16. PubMed
PLEKHM2 deficiency induces impaired mitochondrial clearance and elevated ROS levels in human iPSC-derived cardiomyocytes. Zhang J, Peng Y, Fu W, Wang R, Cao J, Li S, Tian X, Li Z, Hua C, Zhai Y, Liu Y, Liu M, Sun J, Li X, Zhao X, Dong J. Cell Death Discov. 2024 Mar 15;10(1):142. doi: 10.1038/s41420-024-01907-6. PubMed
Generation of ID1/3 knockout human embryonic stem cell lines (WAe009-A-2A and WAe009-A-2B) derived from H9 using CRISPR/Cas9. Li Y, Du M, Jin Z. Stem Cell Res. 2024 Dec;81:103569. doi: 10.1016/j.scr.2024.103569. Epub 2024 Sep 24. PubMed
Establishment of heterozygous LMOD2 knockout human embryonic stem cell line (ZZUNEUi022-A-1) using CRISPR/Cas9 system. Zhang C, Li J, Sai Y, Su H, Jiang Y, Zhang L, Jian L, Zhang H, Guo G, Li E, Li X, Sun L. Stem Cell Res. 2024 Dec;81:103586. doi: 10.1016/j.scr.2024.103586. Epub 2024 Oct 19. PubMed
Mitochondrial transplantation rescues Ca(2+) homeostasis imbalance and myocardial hypertrophy in SLC25A3-related hypertrophic cardiomyopathy. Li S, Zhang J, Fu W, Cao J, Li Z, Tian X, Yang M, Zhao J, Wang C, Liu Y, Liu M, Zhao X, Li X, Dong J, Qi Y. Cell Rep. 2024 Dec 24;43(12):115065. doi: 10.1016/j.celrep.2024.115065. Epub 2024 Dec 12. PubMed
Blocking autophagosome closure manifests the roles of mammalian Atg8-family proteins in phagophore formation and expansion during nutrient starvation. Bui V, Liang X, Ye Y, Giang W, Tian F, Takahashi Y, Wang HG. Autophagy. 2025 May;21(5):1059-1074. doi: 10.1080/15548627.2024.2443300. Epub 2025 Jan 20. PubMed

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