AsCas12a-6xNLS-E174R/S542R (pRG232) Citations (5)

Originally described in: High-performance CRISPR-Cas12a genome editing for combinatorial genetic screening.
Gier RA, Budinich KA, Evitt NH, Cao Z, Freilich ES, Chen Q, Qi J, Lan Y, Kohli RM, Shi J Nat Commun. 2020 Jul 13;11(1):3455. doi: 10.1038/s41467-020-17209-1. PubMed Journal

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Articles Citing AsCas12a-6xNLS-E174R/S542R (pRG232)

Articles
The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade. Cucolo L, Chen Q, Qiu J, Yu Y, Klapholz M, Budinich KA, Zhang Z, Shao Y, Brodsky IE, Jordan MS, Gilliland DG, Zhang NR, Shi J, Minn AJ. Immunity. 2022 Apr 12;55(4):671-685.e10. doi: 10.1016/j.immuni.2022.03.007. PubMed
Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells. Qin K, Huang P, Feng R, Keller CA, Peslak SA, Khandros E, Saari MS, Lan X, Mayuranathan T, Doerfler PA, Abdulmalik O, Giardine B, Chou ST, Shi J, Hardison RC, Weiss MJ, Blobel GA. Nat Genet. 2022 Jun;54(6):874-884. doi: 10.1038/s41588-022-01076-1. Epub 2022 May 26. PubMed
Dissection of the MEF2D-IRF8 transcriptional circuit dependency in acute myeloid leukemia. Pingul BY, Huang H, Chen Q, Alikarami F, Zhang Z, Qi J, Bernt KM, Berger SL, Cao Z, Shi J. iScience. 2022 Sep 15;25(10):105139. doi: 10.1016/j.isci.2022.105139. eCollection 2022 Oct 21. PubMed Associated Plasmids MEF2D-2A-neo
Optimized metrics for orthogonal combinatorial CRISPR screens. Cetin R, Wegner M, Luwisch L, Saud S, Achmedov T, Susser S, Vera-Guapi A, Muller K, Matthess Y, Quandt E, Schaubeck S, Beisel CL, Kaulich M. Sci Rep. 2023 May 6;13(1):7405. doi: 10.1038/s41598-023-34597-8. PubMed Associated Plasmids pLenti_mpx_SpCas9_h7SK(PacI)_U6(I-SceI)_PGK-puro_v2 pLenti_mpx_AsCas12a_h7SK(PacI)_U6(I-SceI)_PGK-puro pLenti_CHyMErA_U6(SpCas9_I-SceI)-(AsCas12_PacI)_PGK-puro pLenti_mpx_AsCas12a(dual-gRNA)_h7SK(PacI-ClaI)_U6(I-SceI-NheI)_PGK-puro pLenti_CHyMErA.v2_U6(SpCas9_I-SceI)-(AsCas12a(dual-gRNA)_PacI-PacI)_PGK-puro
Single-stranded DNA-binding proteins are essential components of the architectural LDB1 protein complex. Wang X, Aboreden NG, Cai Y, Lam JC, Henderson KA, Xiang J, Giardine BM, Hardison RC, Keller CA, Nagarajan L, Brandt SJ, Blobel GA. Mol Cell. 2025 Aug 21;85(16):3074-3089.e8. doi: 10.1016/j.molcel.2025.07.012. Epub 2025 Aug 12. PubMed

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