pMSCV-dCasRx-ALKBH5-PURO Citations (5)

Originally described in: Epitranscriptomic editing of the RNA N6-methyladenosine modification by dCasRx conjugated methyltransferase and demethylase.
Xia Z, Tang M, Ma J, Zhang H, Gimple RC, Prager BC, Tang H, Sun C, Liu F, Lin P, Mei Y, Du R, Rich JN, Xie Q Nucleic Acids Res. 2021 Jul 21;49(13):7361-7374. doi: 10.1093/nar/gkab517. PubMed Journal

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Articles Citing pMSCV-dCasRx-ALKBH5-PURO

Articles
m(6)A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress. Wang L, Zhan G, Maimaitiyiming Y, Su Y, Lin S, Liu J, Su K, Lin J, Shen S, He W, Wang F, Chen J, Sun S, Xue Y, Gu J, Chen X, Zhang J, Zhang L, Wang Q, Chang KJ, Chiou SH, Bjorklund M, Naranmandura H, Cheng X, Hsu CH. Cell Rep. 2022 Oct 25;41(4):111546. doi: 10.1016/j.celrep.2022.111546. PubMed
m (6) A RNA methylation orchestrates transcriptional dormancy during developmental pausing. Collignon E, Cho B, Fothergill-Robinson J, Furlan G, Ross RL, Limbach PA, Ramalho-Santos M. bioRxiv. 2023 Feb 1:2023.01.30.526234. doi: 10.1101/2023.01.30.526234. Preprint. PubMed
m(6)A RNA methylation orchestrates transcriptional dormancy during paused pluripotency. Collignon E, Cho B, Furlan G, Fothergill-Robinson J, Martin SB, McClymont SA, Ross RL, Limbach PA, Ramalho-Santos M. Nat Cell Biol. 2023 Sep;25(9):1279-1289. doi: 10.1038/s41556-023-01212-x. Epub 2023 Sep 7. PubMed
Homozygous EPRS1 missense variant causing hypomyelinating leukodystrophy-15 alters variant-distal mRNA m(6)A site accessibility. Khan D, Ramachandiran I, Vasu K, China A, Khan K, Cumbo F, Halawani D, Terenzi F, Zin I, Long B, Costain G, Blaser S, Carnevale A, Gogonea V, Dutta R, Blankenberg D, Yoon G, Fox PL. Nat Commun. 2024 May 20;15(1):4284. doi: 10.1038/s41467-024-48549-x. PubMed
Synonymous mutations promote tumorigenesis by disrupting m(6)A-dependent mRNA metabolism. Lan Y, Xia Z, Shao Q, Lin P, Lu J, Xiao X, Zheng M, Chen D, Dou Y, Xie Q. Cell. 2025 Apr 3;188(7):1828-1841.e15. doi: 10.1016/j.cell.2025.01.026. Epub 2025 Feb 13. PubMed

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