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AAV N-terminus ABE8e-V106W targeting Pex1-G844D
(Plasmid #247654)

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This material is available to academics and nonprofits only.
Item Catalog # Description Quantity Price (USD)
Plasmid 247654 Standard format: Plasmid sent in bacteria as agar stab 1 $89
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Backbone

  • Vector backbone
    modified pX601
  • Vector type
    AAV, CRISPR

Growth in Bacteria

  • Bacterial Resistance(s)
    Ampicillin, 100 μg/mL
  • Growth Temperature
    37°C
  • Growth Strain(s)
    NEB Stable
  • Copy number
    Unknown

Gene/Insert

  • Gene/Insert name
    N-terminus ABE8e-V106W editor and Pex1-G844D-targeting sgRNA
  • Insert Size (bp)
    4435
  • Promoter CBh

Cloning Information

Resource Information

Terms and Licenses

  • Academic/Nonprofit Terms
  • Industry Terms
    • Not Available to Industry

Trademarks:

  • Zeocin® is an InvivoGen trademark.
How to cite this plasmid ( Back to top)

These plasmids were created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the plasmids were described, and include Addgene in the Materials and Methods of your future publications.

  • For your Materials & Methods section:

    AAV N-terminus ABE8e-V106W targeting Pex1-G844D was a gift from David Liu (Addgene plasmid # 247654 ; http://n2t.net/addgene:247654 ; RRID:Addgene_247654)

  • For your References section:

    In vivo base editing rescues liver pathophysiology and peroxisome dysfunction in a mouse model of Zellweger spectrum disorder. Gao XD, Presa M, Duby JE, Ryan J, Piec P-A, Hsu A, Banskota S, Jiang AY, Chen L, Newby GA, Di Pietro E, Levy JM, Steele BH, Lecordier S, Qin F, Moser AB, Xie J, Gao G, Braverman NE, Zuberi AR, Hacia JG, Lutz CM, Liu DR. Nat. Biomed. Eng (2026). https://doi.org/10.1038/s41551-026-01651-5 10.1038/s41551-026-01651-5
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