pCT302 Citations (6)

Originally described in: Substantial energetic improvement with minimal structural perturbation in a high affinity mutant antibody.
Midelfort KS, Hernandez HH, Lippow SM, Tidor B, Drennan CL, Wittrup KD J Mol Biol. 2004 Oct 22;343(3):685-701. PubMed Journal

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Articles Citing pCT302

Articles
Epistasis in a Fitness Landscape Defined by Antibody-Antigen Binding Free Energy. Adams RM, Kinney JB, Walczak AM, Mora T. Cell Syst. 2019 Jan 23;8(1):86-93.e3. doi: 10.1016/j.cels.2018.12.004. Epub 2019 Jan 2. PubMed
CD4 Inhibits Helper T Cell Activation at Lower Affinity Threshold for Full-Length T Cell Receptors Than Single Chain Signaling Constructs. Johnson DK, Magoffin W, Myers SJ, Finnell JG, Hancock JC, Orton TS, Persaud SP, Christensen KA, Weber KS. Front Immunol. 2021 Jan 19;11:561889. doi: 10.3389/fimmu.2020.561889. eCollection 2020. PubMed
The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design. Saxton RA, Henneberg LT, Calafiore M, Su L, Jude KM, Hanash AM, Garcia KC. Immunity. 2021 Apr 13;54(4):660-672.e9. doi: 10.1016/j.immuni.2021.03.008. PubMed
Engineered IL13 variants direct specificity of IL13Ralpha2-targeted CAR T cell therapy. Stern LA, Gholamin S, Moraga I, Yang X, Saravanakumar S, Cohen JR, Starr R, Aguilar B, Salvary V, Hibbard JC, Kalbasi A, Shepphird JK, O'Hearn J, Garcia KC, Brown CE. Proc Natl Acad Sci U S A. 2022 Aug 16;119(33):e2112006119. doi: 10.1073/pnas.2112006119. Epub 2022 Aug 8. PubMed
Deploying synthetic coevolution and machine learning to engineer protein-protein interactions. Yang A, Jude KM, Lai B, Minot M, Kocyla AM, Glassman CR, Nishimiya D, Kim YS, Reddy ST, Khan AA, Garcia KC. Science. 2023 Jul 28;381(6656):eadh1720. doi: 10.1126/science.adh1720. Epub 2023 Jul 28. PubMed
A Rapid Antibody Enhancement Platform in Saccharomyces cerevisiae Using an Improved, Diversifying CRISPR Base Editor. Cazier AP, Irvin OM, Chavez LS, Dalvi S, Abraham H, Wickramanayake N, Yellayi S, Blazeck J. ACS Synth Biol. 2023 Nov 17;12(11):3287-3300. doi: 10.1021/acssynbio.3c00299. Epub 2023 Oct 24. PubMed

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