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FLAG-Stx17 Citations (12)

Originally described in: The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes.
Itakura E, Kishi-Itakura C, Mizushima N Cell. 2012 Dec 7;151(6):1256-69. doi: 10.1016/j.cell.2012.11.001.
PubMed Journal

Articles Citing FLAG-Stx17

Articles
Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. McLelland GL, Lee SA, McBride HM, Fon EA. J Cell Biol. 2016 Aug 1;214(3):275-91. doi: 10.1083/jcb.201603105. Epub 2016 Jul 25. PubMed
PtdIns(4,5)P2 signaling regulates ATG14 and autophagy. Tan X, Thapa N, Liao Y, Choi S, Anderson RA. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):10896-901. doi: 10.1073/pnas.1523145113. Epub 2016 Sep 12. PubMed
LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes. Hubert V, Peschel A, Langer B, Groger M, Rees A, Kain R. Biol Open. 2016 Oct 15;5(10):1516-1529. doi: 10.1242/bio.018648. PubMed
Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms. Kondo H, Maksimova N, Otomo T, Kato H, Imai A, Asano Y, Kobayashi K, Nojima S, Nakaya A, Hamada Y, Irahara K, Gurinova E, Sukhomyasova A, Nogovicina A, Savvina M, Yoshimori T, Ozono K, Sakai N. Hum Mol Genet. 2016 Dec 23. pii: ddw377. doi: 10.1093/hmg/ddw377. PubMed
BORC coordinates encounter and fusion of lysosomes with autophagosomes. Jia R, Guardia CM, Pu J, Chen Y, Bonifacino JS. Autophagy. 2017 Oct 3;13(10):1648-1663. doi: 10.1080/15548627.2017.1343768. Epub 2017 Aug 21. PubMed
Enteroviruses Remodel Autophagic Trafficking through Regulation of Host SNARE Proteins to Promote Virus Replication and Cell Exit. Corona AK, Saulsbery HM, Corona Velazquez AF, Jackson WT. Cell Rep. 2018 Mar 20;22(12):3304-3314. doi: 10.1016/j.celrep.2018.03.003. PubMed
STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism. Xian H, Yang Q, Xiao L, Shen HM, Liou YC. Nat Commun. 2019 May 3;10(1):2059. doi: 10.1038/s41467-019-10096-1. PubMed
Regulation of Autophagic Flux by the 20S Proteasome. Njomen E, Tepe JJ. Cell Chem Biol. 2019 Sep 19;26(9):1283-1294.e5. doi: 10.1016/j.chembiol.2019.07.002. Epub 2019 Jul 18. PubMed
BAP31 Inhibits Cell Adaptation to ER Stress Conditions, Negatively Regulating Autophagy Induction by Interaction with STX17. Machihara K, Namba T. Cells. 2019 Oct 30;8(11). pii: cells8111350. doi: 10.3390/cells8111350. PubMed
SNARE proteins rescue impaired autophagic flux in Down syndrome. Aivazidis S, Jain A, Rauniyar AK, Anderson CC, Marentette JO, Orlicky DJ, Fritz KS, Harris PS, Siegel D, Maclean KN, Roede JR. PLoS One. 2019 Nov 12;14(11):e0223254. doi: 10.1371/journal.pone.0223254. eCollection 2019. PubMed
PTPN9-mediated dephosphorylation of VTI1B promotes ATG16L1 precursor fusion and autophagosome formation. Chou HY, Lee YT, Lin YJ, Wen JK, Peng WH, Hsieh PL, Lin SY, Hung CC, Chen GC. Autophagy. 2020 Oct 28:1-16. doi: 10.1080/15548627.2020.1838117. PubMed
Direct observation of aggregate-triggered selective autophagy in human cells. Janssen AFJ, Korsten G, Nijenhuis W, Katrukha EA, Kapitein LC. J Cell Sci. 2021 Oct 1;134(19). pii: 271972. doi: 10.1242/jcs.258824. Epub 2021 Oct 6. PubMed

Associated Plasmids

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