Human Lentiviral sgRNA Library - Kinases Citations (4)
Originally described in: Genetic screens in human cells using the CRISPR-Cas9 system.Wang T, Wei JJ, Sabatini DM, Lander ES Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12. PubMed Journal
Articles Citing Human Lentiviral sgRNA Library - Kinases
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The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance pathway. Gul N, Karlsson J, Tangemo C, Linsefors S, Tuyizere S, Perkins R, Ala C, Zou Z, Larsson E, Bergo MO, Lindahl P. Sci Rep. 2019 Oct 11;9(1):14667. doi: 10.1038/s41598-019-51205-w. PubMed |
BTK inhibition sensitizes Acute Lymphoblastic Leukemia to asparaginase by suppressing the Amino Acid Response pathway. Butler M, van Ingen Schenau DS, Yu J, Jenni S, Dobay MP, Hagelaar R, Vervoort BMT, Tee TM, Hoff FW, Meijerink JP, Kornblau SM, Bornhauser B, Bourquin JP, Kuiper RP, van der Meer LT, van Leeuwen FN. Blood. 2021 Jul 19. pii: S0006-4971(21)01372-0. doi: 10.1182/blood.2021011787. PubMed |
Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1. Rauner G, Jin DX, Miller DH, Gierahn TM, Li CM, Sokol ES, Feng YX, Mathis RA, Love JC, Gupta PB, Kuperwasser C. Nat Commun. 2021 Dec 10;12(1):7116. doi: 10.1038/s41467-021-27401-6. PubMed |
AURKA and PLK1 inhibition selectively and synergistically block cell cycle progression in diffuse midline glioma. Metselaar DS, du Chatinier A, Meel MH, Ter Huizen G, Waranecki P, Goulding JR, Bugiani M, Koster J, Kaspers GJL, Hulleman E. iScience. 2022 May 13;25(6):104398. doi: 10.1016/j.isci.2022.104398. eCollection 2022 Jun 17. PubMed |
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