Human Lentiviral sgRNA Library - Nuclear Citations (8)

Originally described in: Genetic screens in human cells using the CRISPR-Cas9 system.
Wang T, Wei JJ, Sabatini DM, Lander ES Science. 2014 Jan 3;343(6166):80-4. doi: 10.1126/science.1246981. Epub 2013 Dec 12. PubMed Journal

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Articles Citing Human Lentiviral sgRNA Library - Nuclear

Articles
CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response. Szlachta K, Kuscu C, Tufan T, Adair SJ, Shang S, Michaels AD, Mullen MG, Fischer NL, Yang J, Liu L, Trivedi P, Stelow EB, Stukenberg PT, Parsons JT, Bauer TW, Adli M. Nat Commun. 2018 Oct 15;9(1):4275. doi: 10.1038/s41467-018-06676-2. PubMed
Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II. Li Y, Liu Y, Xu H, Jiang G, Van der Jeught K, Fang Y, Zhou Z, Zhang L, Frieden M, Wang L, Luo Z, Radovich M, Schneider BP, Deng Y, Liu Y, Huang K, He B, Wang J, He X, Zhang X, Ji G, Lu X. Nat Commun. 2018 Oct 22;9(1):4394. doi: 10.1038/s41467-018-06811-z. PubMed
A CRISPR/Cas9 screen identifies the histone demethylase MINA53 as a novel HIV-1 latency-promoting gene (LPG). Huang H, Kong W, Jean M, Fiches G, Zhou D, Hayashi T, Que J, Santoso N, Zhu J. Nucleic Acids Res. 2019 Jun 5. pii: 5511480. doi: 10.1093/nar/gkz493. PubMed
CRISPR Cas9 in Pancreatic Cancer Research. Yang H, Bailey P, Pilarsky C. Front Cell Dev Biol. 2019 Oct 18;7:239. doi: 10.3389/fcell.2019.00239. eCollection 2019. PubMed
Targeted CRISPR screening identifies PRMT5 as synthetic lethality combinatorial target with gemcitabine in pancreatic cancer cells. Wei X, Yang J, Adair SJ, Ozturk H, Kuscu C, Lee KY, Kane WJ, O'Hara PE, Liu D, Demirlenk YM, Habieb AH, Yilmaz E, Dutta A, Bauer TW, Adli M. Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28068-28079. doi: 10.1073/pnas.2009899117. Epub 2020 Oct 23. PubMed
An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase. Zhou Z, Li Y, Xu H, Xie X, He Z, Lin S, Li R, Jin S, Cui J, Hu H, Liu F, Wu S, Ma W, Songyang Z. iScience. 2022 Jan 25;25(2):103813. doi: 10.1016/j.isci.2022.103813. eCollection 2022 Feb 18. PubMed
CRISPR-Cas and CRISPR-based screening system for precise gene editing and targeted cancer therapy. Qin M, Deng C, Wen L, Luo G, Meng Y. J Transl Med. 2024 May 30;22(1):516. doi: 10.1186/s12967-024-05235-2. PubMed
Leveraging Circular Polymerization and Extension Cloning (CPEC) Method for Construction of CRISPR Screening Libraries. Dayanc B, Eris S, Senturk S. Bio Protoc. 2025 Feb 20;15(4):e5183. doi: 10.21769/BioProtoc.5183. eCollection 2025 Feb 20. PubMed

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