pAAV/D374Y-hPCSK9 Citations (5)
Originally described in: Induction of atherosclerosis in mice and hamsters without germline genetic engineering.Bjorklund MM, Hollensen AK, Hagensen MK, Dagnaes-Hansen F, Christoffersen C, Mikkelsen JG, Bentzon JF Circ Res. 2014 May 23;114(11):1684-9. doi: 10.1161/CIRCRESAHA.114.302937. Epub 2014 Mar 27. PubMed Journal
Articles Citing pAAV/D374Y-hPCSK9
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Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research.
Jarrett KE, Lee C, De Giorgi M, Hurley A, Gillard BK, Doerfler AM, Li A, Pownall HJ, Bao G, Lagor WR.
Arterioscler Thromb Vasc Biol. 2018 Jul 19. pii: ATVBAHA.118.311221. doi: 10.1161/ATVBAHA.118.311221.
PubMed
Associated Plasmids |
| Receptor-Mediated ER Export of Lipoproteins Controls Lipid Homeostasis in Mice and Humans. Wang X, Wang H, Xu B, Huang D, Nie C, Pu L, Zajac GJM, Yan H, Zhao J, Shi F, Emmer BT, Lu J, Wang R, Dong X, Dai J, Zhou W, Wang C, Gao G, Wang Y, Willer C, Lu X, Zhu Y, Chen XW. Cell Metab. 2021 Feb 2;33(2):350-366.e7. doi: 10.1016/j.cmet.2020.10.020. Epub 2020 Nov 12. PubMed |
| PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer. Rademaker G, Hernandez GA, Seo Y, Dahal S, Miller-Phillips L, Li AL, Peng XL, Luan C, Qiu L, Liegeois MA, Wang B, Wen KW, Kim GE, Collisson EA, Kruger SF, Boeck S, Ormanns S, Guenther M, Heinemann V, Haas M, Looney MR, Yeh JJ, Zoncu R, Perera RM. Nature. 2025 Jul;643(8074):1381-1390. doi: 10.1038/s41586-025-09017-8. Epub 2025 May 21. PubMed |
| Cytoplasmic and nuclear NFATc3 cooperatively contributes to vascular smooth muscle cell dysfunction and drives aortic aneurysm and dissection. Liu X, Zhao L, Liu D, Zhao L, Tuo Y, Peng Q, Huang F, Song Z, Niu C, He X, Xu Y, Wan J, Zhu P, Jian Z, Guo J, Liu Y, Lu J, Liang S, Zheng S. Acta Pharm Sin B. 2025 Jul;15(7):3663-3684. doi: 10.1016/j.apsb.2025.05.016. Epub 2025 May 21. PubMed |
| Engineering chimeric PCSK9 for a vaccine against atherosclerosis. Malensek S, Lainscek D, Esih H, Orehek S, Fink T, Urbanc AG, Blinc A, Jerala R. Mol Ther Methods Clin Dev. 2025 Jul 12;33(3):101535. doi: 10.1016/j.omtm.2025.101535. eCollection 2025 Sep 11. PubMed |
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