Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

pCMV HA hRb delta CDK
(Plasmid #58906)


Item Catalog # Description Quantity Price (USD)
Plasmid 58906 Standard format: Plasmid sent in bacteria as agar stab 1 $65

This material is available to academics and nonprofits only.


Growth in Bacteria

  • Bacterial Resistance(s)
  • Growth Temperature
  • Growth Strain(s)
  • Copy number
    High Copy


  • Gene/Insert name
  • Alt name
    retinoblastoma tumor suppressor protein
  • Species
    H. sapiens (human)
  • Insert Size (bp)
  • Mutation
    all 15 Ser/Thr Cdk acceptor sites changed to Ala, with Ser567 left unaltered (T5, S230A, S249A, T252A, T356A, T373A, S608A, S612A, S780A, S788A, S795A, S807A, S811A, T821A, T826A)
  • Entrez Gene
    RB1 (a.k.a. OSRC, PPP1R130, RB, p105-Rb, pRb, pp110)
  • Promoter CMV
  • Tag / Fusion Protein
    • HA (N terminal on insert)

Cloning Information

Resource Information

How to cite this plasmid ( Back to top)

These plasmids were created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the plasmids were described, and include Addgene in the Materials and Methods of your future publications.

  • For your Materials & Methods section:

    pCMV HA hRb delta CDK was a gift from Steven Dowdy (Addgene plasmid # 58906 ; ; RRID:Addgene_58906)
  • For your References section:

    Cyclin D activates the Rb tumor suppressor by mono-phosphorylation. Narasimha AM, Kaulich M, Shapiro GS, Choi YJ, Sicinski P, Dowdy SF. Elife. 2014 May 29:e02872. doi: 10.7554/eLife.02872. 10.7554/eLife.02872 PubMed 24876129