4XCLEAR-luciferase reporter Citations (13)

Originally described in: Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA.
Cortes CJ, Miranda HC, Frankowski H, Batlevi Y, Young JE, Le A, Ivanov N, Sopher BL, Carromeu C, Muotri AR, Garden GA, La Spada AR Nat Neurosci. 2014 Sep;17(9):1180-9. doi: 10.1038/nn.3787. Epub 2014 Aug 10. PubMed Journal

---

Articles Citing 4XCLEAR-luciferase reporter

Articles
Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling. Segala G, Bennesch MA, Ghahhari NM, Pandey DP, Echeverria PC, Karch F, Maeda RK, Picard D. Nat Commun. 2019 Apr 23;10(1):1833. doi: 10.1038/s41467-019-09800-y. PubMed
Rapamycin directly activates lysosomal mucolipin TRP channels independent of mTOR. Zhang X, Chen W, Gao Q, Yang J, Yan X, Zhao H, Su L, Yang M, Gao C, Yao Y, Inoki K, Li D, Shao R, Wang S, Sahoo N, Kudo F, Eguchi T, Ruan B, Xu H. PLoS Biol. 2019 May 21;17(5):e3000252. doi: 10.1371/journal.pbio.3000252. eCollection 2019 May. PubMed
Optical induction of autophagy via Transcription factor EB (TFEB) reduces pathological tau in neurons. Binder JL, Chander P, Deretic V, Weick JP, Bhaskar K. PLoS One. 2020 Mar 24;15(3):e0230026. doi: 10.1371/journal.pone.0230026. eCollection 2020. PubMed
Coxsackievirus B3 targets TFEB to disrupt lysosomal function. Mohamud Y, Tang H, Xue YC, Liu H, Ng CS, Bahreyni A, Luo H. Autophagy. 2021 Mar 10:1-15. doi: 10.1080/15548627.2021.1896925. PubMed
AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3. Paquette M, El-Houjeiri L, C Zirden L, Puustinen P, Blanchette P, Jeong H, Dejgaard K, Siegel PM, Pause A. Autophagy. 2021 Mar 18:1-19. doi: 10.1080/15548627.2021.1898748. PubMed
Folliculin impairs breast tumor growth by repressing TFE3-dependent induction of the Warburg effect and angiogenesis. El-Houjeiri L, Biondini M, Paquette M, Kuasne H, Pacis A, Park M, Siegel PM, Pause A. J Clin Invest. 2021 Nov 15;131(22). pii: 144871. doi: 10.1172/JCI144871. PubMed
A prion-like domain of TFEB mediates the co-aggregation of TFEB and mHTT. Yang J, Xu H, Zhang C, Yang X, Cai W, Chen X. Autophagy. 2022 Jun 1:1-7. doi: 10.1080/15548627.2022.2083857. PubMed
Reduction of nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43-related neurodegeneration. Tejwani L, Jung Y, Kokubu H, Sowmithra S, Ni L, Lee C, Sanders B, Lee PJ, Xiang Y, Luttik K, Soriano A, Yoon J, Park J, Ro HH, Ju H, Liao C, Tieze SM, Rigo F, Jafar-Nejad P, Lim J. J Clin Invest. 2023 Aug 15;133(16):e138207. doi: 10.1172/JCI138207. PubMed
Design and validation of a reporter mouse to study the dynamic regulation of TFEB and TFE3 activity through in vivo imaging techniques. Brunialti E, Rizzi N, Pinto-Costa R, Villa A, Panzeri A, Meda C, Rebecchi M, Di Monte DA, Ciana P. Autophagy. 2024 Aug;20(8):1879-1894. doi: 10.1080/15548627.2024.2334111. Epub 2024 Mar 27. PubMed
TFEB triggers a matrix degradation and invasion program in triple-negative breast cancer cells upon mTORC1 repression. Remy D, Antoine-Bally S, de Toqueville S, Jolly C, Mace AS, Champenois G, Nemati F, Brito I, Raynal V, Priya A, Berlioz A, Dahmani A, Nicolas A, Meseure D, Marangoni E, Chavrier P. Dev Cell. 2025 Apr 7;60(7):1018-1035.e8. doi: 10.1016/j.devcel.2024.12.005. Epub 2024 Dec 26. PubMed
Transcription factor EB (TFEB) activity increases resistance of TNBC stem cells to metabolic stress. Soleimani M, Duchow M, Goyal R, Somma A, Kaoud TS, Dalby KN, Kowalski J, Eckhardt SG, Van Den Berg C. Life Sci Alliance. 2025 Jan 15;8(3):e202302259. doi: 10.26508/lsa.202302259. Print 2025 Mar. PubMed
Evolutionary conserved regulation of TFEB stability by the E3 ubiquitin ligase WWP2 modulates response to stress in vivo. Garcia-Sanchez JA, Bonnet E, Loubatier C, Doye A, Paillier G, Segui F, Larbret F, Chaintreuil P, Batistic L, Torre C, Deckert M, Polanowska J, Munro P, Boyer L, Visvikis O. iScience. 2025 Jan 17;28(2):111838. doi: 10.1016/j.isci.2025.111838. eCollection 2025 Feb 21. PubMed
Sodium butyrate ameliorates renal tubular lipid accumulation through a protein phosphatase 2A/transcription factor EB axis in diabetic nephropathy. Tao J, Ai S, Wang Y, Liu Y, Zhou J, Liu Q, Wang X, Li D, Li X, Wang L, Hou J, Peng L, Wang Z. Br J Pharmacol. 2025 Dec 3. doi: 10.1111/bph.70261. PubMed

If you have published an article using this material, please email us at to have your article added to this page.