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pKLV2-EF1a-Cas9Bsd-W Citations (8)

Plasmid Article: A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.
Tzelepis K, Koike-Yusa H, De Braekeleer E, Li Y, Metzakopian E, Dovey OM, Mupo A, Grinkevich V, Li M, Mazan M, Gozdecka M, Ohnishi S, Cooper J, Patel M, McKerrell T, Chen B, Domingues AF, Gallipoli P, Teichmann S, Ponstingl H, McDermott U, Saez-Rodriguez J, Huntly BJ, Iorio F, Pina C, Vassiliou GS, Yusa K Cell Rep. 2016 Oct 18;17(4):1193-1205. doi: 10.1016/j.celrep.2016.09.079.
PubMed Journal

Articles Citing pKLV2-EF1a-Cas9Bsd-W

Genome-scale identification of cellular pathways required for cell surface recognition. Sharma S, Bartholdson SJ, Couch ACM, Yusa K, Wright GJ. Genome Res. 2018 Sep;28(9):1372-1382. doi: 10.1101/gr.231183.117. Epub 2018 Jun 18. PubMed
Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting. Iorio F, Behan FM, Goncalves E, Bhosle SG, Chen E, Shepherd R, Beaver C, Ansari R, Pooley R, Wilkinson P, Harper S, Butler AP, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ. BMC Genomics. 2018 Aug 13;19(1):604. doi: 10.1186/s12864-018-4989-y. PubMed
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens. Behan FM, Iorio F, Picco G, Goncalves E, Beaver CM, Migliardi G, Santos R, Rao Y, Sassi F, Pinnelli M, Ansari R, Harper S, Jackson DA, McRae R, Pooley R, Wilkinson P, van der Meer D, Dow D, Buser-Doepner C, Bertotti A, Trusolino L, Stronach EA, Saez-Rodriguez J, Yusa K, Garnett MJ. Nature. 2019 Apr;568(7753):511-516. doi: 10.1038/s41586-019-1103-9. Epub 2019 Apr 10. PubMed
A molecular triage process mediated by RING finger protein 126 and BCL2-associated athanogene 6 regulates degradation of G0/G1 switch gene 2. Kamikubo K, Kato H, Kioka H, Yamazaki S, Tsukamoto O, Nishida Y, Asano Y, Imamura H, Kawahara H, Shintani Y, Takashima S. J Biol Chem. 2019 Oct 4;294(40):14562-14573. doi: 10.1074/jbc.RA119.008544. Epub 2019 Aug 1. PubMed
Generation of Monoclonal iPSC Lines with Stable Cas9 Expression and High Cas9 Activity. Liao JQ, Zhou G, Zhou Y. Methods Mol Biol. 2020 Jun 22. doi: 10.1007/7651_2020_304. PubMed
Cell Surface Receptor Identification Using Genome-Scale CRISPR/Cas9 Genetic Screens. Sharma S, Wright GJ. J Vis Exp. 2020 Jun 6;(160). doi: 10.3791/60803. PubMed
Analysis of CRISPR-Cas9 screens identifies genetic dependencies in melanoma. Christodoulou E, Rashid M, Pacini C, Droop A, Robertson H, Groningen TV, Teunisse AFAS, Iorio F, Jochemsen AG, Adams DJ, Doorn RV. Pigment Cell Melanoma Res. 2021 Jan;34(1):122-131. doi: 10.1111/pcmr.12919. Epub 2020 Sep 7. PubMed
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway. Chai AWY, Yee PS, Price S, Yee SM, Lee HM, Tiong VK, Goncalves E, Behan FM, Bateson J, Gilbert J, Tan AC, McDermott U, Garnett MJ, Cheong SC. Elife. 2020 Sep 29;9. pii: 57761. doi: 10.7554/eLife.57761. PubMed

Associated Plasmids

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