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pLoxP-DHFR-mCherry Citations (10)

Originally described in: Analysis of non-canonical calcium dependent protein kinases in Toxoplasma gondii by targeted gene deletion using CRISPR/Cas9.
Long S, Wang Q, Sibley LD Infect Immun. 2016 Jan 11. doi: 10.1128/IAI.01173-15
PubMed Journal

Articles Citing pLoxP-DHFR-mCherry

Articles
Toxoplasma CRISPR/Cas9 constructs are functional for gene disruption in Neospora caninum. Arranz-Solis D, Regidor-Cerrillo J, Lourido S, Ortega-Mora LM, Saeij JPJ. Int J Parasitol. 2018 Jul;48(8):597-600. doi: 10.1016/j.ijpara.2018.03.002. Epub 2018 Apr 3. PubMed
Toxoplasma GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11. Mukhopadhyay D, Arranz-Solis D, Saeij JPJ. PLoS Pathog. 2020 May 26;16(5):e1008586. doi: 10.1371/journal.ppat.1008586. eCollection 2020 May. PubMed
Naive CD8 T cell IFNgamma responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5. Kongsomboonvech AK, Rodriguez F, Diep AL, Justice BM, Castallanos BE, Camejo A, Mukhopadhyay D, Taylor GA, Yamamoto M, Saeij JPJ, Reese ML, Jensen KDC. PLoS Pathog. 2020 Aug 27;16(8):e1008327. doi: 10.1371/journal.ppat.1008327. eCollection 2020 Aug. PubMed
Auranofin Resistance in Toxoplasma gondii Decreases the Accumulation of Reactive Oxygen Species but Does Not Target Parasite Thioredoxin Reductase. Ma CI, Tirtorahardjo JA, Jan S, Schweizer SS, Rosario SAC, Du Y, Zhang JJ, Morrissette NS, Andrade RM. Front Cell Infect Microbiol. 2021 Mar 19;11:618994. doi: 10.3389/fcimb.2021.618994. eCollection 2021. PubMed
Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins. Wang X, Fu Y, Beatty WL, Ma M, Brown A, Sibley LD, Zhang R. Nat Commun. 2021 May 24;12(1):3065. doi: 10.1038/s41467-021-23351-1. PubMed
Transcriptional modification of host cells harboring Toxoplasma gondii bradyzoites prevents IFN gamma-mediated cell death. Seizova S, Ruparel U, Garnham AL, Bader SM, Uboldi AD, Coffey MJ, Whitehead LW, Rogers KL, Tonkin CJ. Cell Host Microbe. 2022 Feb 9;30(2):232-247.e6. doi: 10.1016/j.chom.2021.11.012. Epub 2021 Dec 17. PubMed
NcGRA7 and NcROP40 Play a Role in the Virulence of Neospora caninum in a Pregnant Mouse Model. Rico-San Roman L, Amieva R, Regidor-Cerrillo J, Garcia-Sanchez M, Collantes-Fernandez E, Pastor-Fernandez I, Saeij JPJ, Ortega-Mora LM, Horcajo P. Pathogens. 2022 Aug 31;11(9):998. doi: 10.3390/pathogens11090998. PubMed
Functional screening reveals Toxoplasma prenylated proteins required for endocytic trafficking and rhoptry protein sorting. Wang QQ, Sun M, Tang T, Lai DH, Liu J, Maity S, He K, Wu XT, Yang J, Li YB, Tang XY, Ding HY, Hide G, Distefano M, Lun ZR, Zhu XQ, Long S. mBio. 2023 Aug 31;14(4):e0130923. doi: 10.1128/mbio.01309-23. Epub 2023 Aug 7. PubMed
NcROP2 deletion reduces Neospora caninum virulence by altering parasite stage differentiation and hijacking host immune response. Amieva R, Coronado M, Powell J, Arranz-Solis D, Hassan MA, Collantes-Fernandez E, Ortega-Mora LM, Horcajo P. Front Immunol. 2025 Aug 12;16:1617570. doi: 10.3389/fimmu.2025.1617570. eCollection 2025. PubMed
Loss of NcBPK1 impairs bradyzoite differentiation and enhances virulence in Neospora caninum. Amieva R, Rico-San Roman L, Pastor-Fernandez I, Hemphill A, Boubaker G, Collantes-Fernandez E, Ortega-Mora LM, Horcajo P. Parasit Vectors. 2025 Oct 21;18(1):422. doi: 10.1186/s13071-025-07076-4. PubMed

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