pUC57-mitoLbNOX Citations (12)
Originally described in: Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio.Titov DV, Cracan V, Goodman RP, Peng J, Grabarek Z, Mootha VK Science. 2016 Apr 8;352(6282):231-5. doi: 10.1126/science.aad4017. Epub 2016 Apr 7. PubMed Journal
Articles Citing pUC57-mitoLbNOX
| Articles |
|---|
| Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen. Vardhana SA, Hwee MA, Berisa M, Wells DK, Yost KE, King B, Smith M, Herrera PS, Chang HY, Satpathy AT, van den Brink MRM, Cross JR, Thompson CB. Nat Immunol. 2020 Sep;21(9):1022-1033. doi: 10.1038/s41590-020-0725-2. Epub 2020 Jul 13. PubMed |
Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment.
Balderas E, Eberhardt DR, Lee S, Pleinis JM, Sommakia S, Balynas AM, Yin X, Parker MC, Maguire CT, Cho S, Szulik MW, Bakhtina A, Bia RD, Friederich MW, Locke TM, Van Hove JLK, Drakos SG, Sancak Y, Tristani-Firouzi M, Franklin S, Rodan AR, Chaudhuri D.
Nat Commun. 2022 May 19;13(1):2769. doi: 10.1038/s41467-022-30236-4.
PubMed
Associated Plasmids |
| Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells. Altea-Manzano P, Vandekeere A, Edwards-Hicks J, Roldan M, Abraham E, Lleshi X, Guerrieri AN, Berardi D, Wills J, Junior JM, Pantazi A, Acosta JC, Sanchez-Martin RM, Fendt SM, Martin-Hernandez M, Finch AJ. Mol Cell. 2022 Dec 1;82(23):4537-4547.e7. doi: 10.1016/j.molcel.2022.10.005. Epub 2022 Nov 2. PubMed |
| Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade. Mahmood M, Liu EM, Shergold AL, Tolla E, Tait-Mulder J, Uribe AH, Shokry E, Young AL, Lilla S, Kim M, Park T, Manchon JL, Rodriguez-Antona C, Walters RC, Springett RJ, Blaza JN, Zanivan S, Sumpton D, Roberts EW, Reznik E, Gammage PA. bioRxiv. 2023 Mar 23:2023.03.21.533091. doi: 10.1101/2023.03.21.533091. Preprint. PubMed |
| Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma. Mahmood M, Liu EM, Shergold AL, Tolla E, Tait-Mulder J, Huerta-Uribe A, Shokry E, Young AL, Lilla S, Kim M, Park T, Boscenco S, Manchon JL, Rodriguez-Antona C, Walters RC, Springett RJ, Blaza JN, Mitchell L, Blyth K, Zanivan S, Sumpton D, Roberts EW, Reznik E, Gammage PA. Nat Cancer. 2024 Apr;5(4):659-672. doi: 10.1038/s43018-023-00721-w. Epub 2024 Jan 29. PubMed |
| Respiratory complex I-mediated NAD(+) regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21(Cip1) expression by SIRT3 and SIRT7. Higurashi M, Mori K, Nakagawa H, Uchida M, Ishikawa F, Shibanuma M. Mol Oncol. 2025 Jun;19(6):1775-1796. doi: 10.1002/1878-0261.13808. Epub 2025 Jan 28. PubMed |
| Lactate dehydrogenase A-coupled NAD(+) regeneration is critical for acute myeloid leukemia cell survival. Erdem A, Kaye S, Caligiore F, Johanns M, Leguay F, Schuringa JJ, Ito K, Bommer G, van Gastel N. bioRxiv [Preprint]. 2025 Mar 7:2025.03.03.641255. doi: 10.1101/2025.03.03.641255. PubMed |
Genetically encoded tool for manipulation of DeltaPsim identifies its role as the driver of ISR induced by ATP synthase dysfunction.
Choe M, Ekvik AE, Stalnaker G, Shin HR, Titov DV.
Cell Chem Biol. 2025 Apr 17;32(4):620-630.e6. doi: 10.1016/j.chembiol.2025.03.007.
PubMed
Associated Plasmids |
| Lactate dehydrogenase A-coupled NAD(+) regeneration is critical for acute myeloid leukemia cell survival. Erdem A, Kaye S, Caligiore F, Johanns M, Leguay F, Schuringa JJ, Ito K, Bommer G, van Gastel N. Cancer Metab. 2025 May 19;13(1):22. doi: 10.1186/s40170-025-00392-4. PubMed |
| Estrogens protect bone mass by inhibiting NAD(+) metabolism in osteoclasts. Marques-Carvalho A, Adam GO, Chalke A, Resende-Coelho A, Reyes-Castro O, Warren A, Grilo LF, Chini CC, Stronach B, Alturkmani F, Ambrogini E, Chini EN, Kim HN, Almeida M. bioRxiv [Preprint]. 2025 Jul 16:2025.07.11.664289. doi: 10.1101/2025.07.11.664289. PubMed |
| The mevalonate pathway couples lipid metabolism to amino acid synthesis via ubiquinone-dependent redox control. Nguyen TT, Bansal M, Ding J, Sudarshan S, Ding HF. bioRxiv [Preprint]. 2025 Aug 12:2025.08.10.669191. doi: 10.1101/2025.08.10.669191. PubMed |
| Genetic modulation of mitochondrial NAD+ regeneration does not prevent dopaminergic neuron dysfunction caused by mitochondrial complex I impairment. D'Alessandro KB, Zampese E, Blum JLE, Kuusik B, Palmiotti A, Davidson SM, Reczek CR, Surmeier DJ, Chandel NS. Front Cell Dev Biol. 2025 Sep 25;13:1650462. doi: 10.3389/fcell.2025.1650462. eCollection 2025. PubMed |
If you have published an article using this material, please email us at [email protected] to have your article added to this page.