pGEX-4T-3-mR7BD Citations (11)

Originally described in: Rab7 activation by growth factor withdrawal contributes to the induction of apoptosis.
Romero Rosales K, Peralta ER, Guenther GG, Wong SY, Edinger AL Mol Biol Cell. 2009 Jun;20(12):2831-40. doi: 10.1091/mbc.E08-09-0911. Epub 2009 Apr 22. PubMed Journal

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Articles Citing pGEX-4T-3-mR7BD

Articles
A SUMOylation-dependent switch of RAB7 governs intracellular life and pathogenesis of Salmonella Typhimurium. Mohapatra G, Gaur P, Mujagond P, Singh M, Rana S, Pratap S, Kaur N, Verma S, Krishnan V, Singh N, Srikanth CV. J Cell Sci. 2019 Jan 11;132(1). pii: jcs.222612. doi: 10.1242/jcs.222612. PubMed
Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson's disease. Kim S, Wong YC, Gao F, Krainc D. Nat Commun. 2021 Mar 22;12(1):1807. doi: 10.1038/s41467-021-22113-3. PubMed
Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation. Li T, Fu B, Zhang X, Zhou Y, Yang M, Cao M, Chen Y, Tan Y, Hu R. Cancer Immunol Res. 2021 Sep;9(9):1008-1023. doi: 10.1158/2326-6066.CIR-20-1043. Epub 2021 Jul 20. PubMed
Parkin regulates amino acid homeostasis at mitochondria-lysosome (M/L) contact sites in Parkinson's disease. Peng W, Schroder LF, Song P, Wong YC, Krainc D. Sci Adv. 2023 Jul 21;9(29):eadh3347. doi: 10.1126/sciadv.adh3347. Epub 2023 Jul 19. PubMed
Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP. Mulligan RJ, Magaj MM, Digilio L, Redemann S, Yap CC, Winckler B. bioRxiv [Preprint]. 2024 Feb 17:2023.10.24.563658. doi: 10.1101/2023.10.24.563658. PubMed
Serotonin Receptor HTR2B Facilitates Colorectal Cancer Metastasis via CREB1-ZEB1 Axis-Mediated Epithelial-Mesenchymal Transition. Li T, Wei L, Zhang X, Fu B, Zhou Y, Yang M, Cao M, Chen Y, Tan Y, Shi Y, Wu L, Xuan C, Du Q, Hu R. Mol Cancer Res. 2024 Jun 4;22(6):538-554. doi: 10.1158/1541-7786.MCR-23-0513. PubMed
Collapse of late endosomal pH elicits a rapid Rab7 response via the V-ATPase and RILP. Mulligan RJ, Magaj MM, Digilio L, Redemann S, Yap CC, Winckler B. J Cell Sci. 2024 May 1;137(9):jcs261765. doi: 10.1242/jcs.261765. Epub 2024 May 13. PubMed
IDO1 inhibitors are synergistic with CXCL10 agonists in inhibiting colon cancer growth. Yang M, Cao M, Zhang X, Fu B, Chen Y, Tan Y, Xuan C, Su Y, Tan D, Hu R. Biomed Pharmacother. 2024 Oct;179:117412. doi: 10.1016/j.biopha.2024.117412. Epub 2024 Sep 9. PubMed
Hyperactivation of RAB5 disrupts the endosomal Rab cascade leading to endolysosomal dysregulation in Down syndrome: A necessary role for increased APP gene dose. Chen XQ, Zuo X, Becker A, Mobley WC. Alzheimers Dement. 2025 May;21(5):e70046. doi: 10.1002/alz.70046. PubMed
PKD3 localizes to late endosomes to maintain Rab7-dependent endolysosomal homeostasis. Gutierrez-Galindo E, Jursik K, Frey Y, Meyer F, Hausser A. iScience. 2025 Aug 20;28(9):113408. doi: 10.1016/j.isci.2025.113408. eCollection 2025 Sep 19. PubMed
Rab7a is required to degrade select blood-brain barrier junctional proteins after ischemic stroke. Cottarelli A, Jamoul D, Tuohy MC, Shahriar S, Glendinning M, Prochilo G, Edinger AL, Arac A, Agalliu D. Acta Neuropathol Commun. 2025 Sep 29;13(1):203. doi: 10.1186/s40478-025-02125-6. PubMed

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