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pBIG1a Citations (10)

Originally described in: biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes.
Weissmann F, Petzold G, VanderLinden R, Huis In 't Veld PJ, Brown NG, Lampert F, Westermann S, Stark H, Schulman BA, Peters JM Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2564-9. doi: 10.1073/pnas.1604935113. Epub 2016 Apr 25.
PubMed Journal

Articles Citing pBIG1a

Articles
Multivalency of NDC80 in the outer kinetochore is essential to track shortening microtubules and generate forces. Volkov VA, Huis In 't Veld PJ, Dogterom M, Musacchio A. Elife. 2018 Apr 9;7. pii: 36764. doi: 10.7554/eLife.36764. PubMed
Reconstitution of a 26-Subunit Human Kinetochore Reveals Cooperative Microtubule Binding by CENP-OPQUR and NDC80. Pesenti ME, Prumbaum D, Auckland P, Smith CM, Faesen AC, Petrovic A, Erent M, Maffini S, Pentakota S, Weir JR, Lin YC, Raunser S, McAinsh AD, Musacchio A. Mol Cell. 2018 Sep 20;71(6):923-939.e10. doi: 10.1016/j.molcel.2018.07.038. Epub 2018 Aug 30. PubMed
BUB1 and CENP-U, Primed by CDK1, Are the Main PLK1 Kinetochore Receptors in Mitosis. Singh P, Pesenti ME, Maffini S, Carmignani S, Hedtfeld M, Petrovic A, Srinivasamani A, Bange T, Musacchio A. Mol Cell. 2021 Jan 7;81(1):67-87.e9. doi: 10.1016/j.molcel.2020.10.040. Epub 2020 Nov 27. PubMed
A Role for SMARCB1 in Synovial Sarcomagenesis Reveals That SS18-SSX Induces Canonical BAF Destruction. Li J, Mulvihill TS, Li L, Barrott JJ, Nelson ML, Wagner L, Lock IC, Pozner A, Lambert SL, Ozenberger BB, Ward MB, Grossmann AH, Liu T, Banito A, Cairns BR, Jones KB. Cancer Discov. 2021 Oct;11(10):2620-2637. doi: 10.1158/2159-8290.CD-20-1219. Epub 2021 Jun 2. PubMed
Cohesin mediates DNA loop extrusion by a "swing and clamp" mechanism. Bauer BW, Davidson IF, Canena D, Wutz G, Tang W, Litos G, Horn S, Hinterdorfer P, Peters JM. Cell. 2021 Oct 14;184(21):5448-5464.e22. doi: 10.1016/j.cell.2021.09.016. Epub 2021 Oct 7. PubMed
Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms. Nagasaka K, Davidson IF, Stocsits RR, Tang W, Wutz G, Batty P, Panarotto M, Litos G, Schleiffer A, Gerlich DW, Peters JM. Mol Cell. 2023 Sep 7;83(17):3049-3063.e6. doi: 10.1016/j.molcel.2023.07.024. Epub 2023 Aug 16. PubMed
Modularity of PRC1 Composition and Chromatin Interaction define Condensate Properties. Niekamp S, Marr SK, Oei TA, Subramanian R, Kingston RE. bioRxiv [Preprint]. 2023 Nov 1:2023.10.26.564217. doi: 10.1101/2023.10.26.564217. PubMed
Modularity of PRC1 composition and chromatin interaction define condensate properties. Niekamp S, Marr SK, Oei TA, Subramanian R, Kingston RE. Mol Cell. 2024 May 2;84(9):1651-1666.e12. doi: 10.1016/j.molcel.2024.03.001. Epub 2024 Mar 22. PubMed
PAF1C-mediated activation of CDK12/13 kinase activity is critical for CTD phosphorylation and transcript elongation. Lopez Martinez D, Todorovski I, Noe Gonzalez M, Rusimbi C, Blears D, Khallou N, Han Z, Dirac-Svejstrup AB, Svejstrup JQ. Mol Cell. 2025 May 15;85(10):1952-1967.e8. doi: 10.1016/j.molcel.2025.04.012. Epub 2025 May 1. PubMed

Associated Plasmids

Cohesin supercoils DNA during loop extrusion. Davidson IF, Barth R, Nagasaka K, Tang W, Wutz G, Horn S, Janissen R, Stocsits RR, Chlosta E, Bauer BW, Dekker C, Peters JM. Cell Rep. 2025 Jun 24;44(6):115856. doi: 10.1016/j.celrep.2025.115856. Epub 2025 Jun 13. PubMed

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