Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pY109 (lenti-LbCpf1) Citations (6)

Originally described in: Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array.
Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F Nat Biotechnol. 2017 Jan;35(1):31-34. doi: 10.1038/nbt.3737. Epub 2016 Dec 5.
PubMed Journal

Articles Citing pY109 (lenti-LbCpf1)

Articles
Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion. Chow RD, Kim HR, Chen S. Nat Commun. 2018 May 15;9(1):1903. doi: 10.1038/s41467-018-04158-z. PubMed

Associated Plasmids

A Single H1 Promoter Can Drive Both Guide RNA and Endonuclease Expression in the CRISPR-Cas9 System. Gao Z, Herrera-Carrillo E, Berkhout B. Mol Ther Nucleic Acids. 2019 Mar 1;14:32-40. doi: 10.1016/j.omtn.2018.10.016. Epub 2018 Nov 1. PubMed
Multiplexed orthogonal genome editing and transcriptional activation by Cas12a. Breinig M, Schweitzer AY, Herianto AM, Revia S, Schaefer L, Wendler L, Cobos Galvez A, Tschaharganeh DF. Nat Methods. 2019 Jan;16(1):51-54. doi: 10.1038/s41592-018-0262-1. Epub 2018 Dec 17. PubMed

Associated Plasmids

Extinction of all infectious HIV in cell culture by the CRISPR-Cas12a system with only a single crRNA. Gao Z, Fan M, Das AT, Herrera-Carrillo E, Berkhout B. Nucleic Acids Res. 2020 Jun 4;48(10):5527-5539. doi: 10.1093/nar/gkaa226. PubMed
A combinatorial CRISPR-Cas12a attack on HIV DNA. Fan M, Berkhout B, Herrera-Carrillo E. Mol Ther Methods Clin Dev. 2022 Feb 26;25:43-51. doi: 10.1016/j.omtm.2022.02.010. eCollection 2022 Jun 9. PubMed
CRISPR-Cas12b enables a highly efficient attack on HIV proviral DNA in T cell cultures. Fan M, Bao Y, Berkhout B, Herrera-Carrillo E. Biomed Pharmacother. 2023 Sep;165:115046. doi: 10.1016/j.biopha.2023.115046. Epub 2023 Jun 28. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.