N-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice.
Andries O, Cafferty SM, De Smedt SC, Weiss R, Sanders NN, Kitada T
J Control Release. 2015 Sep 2. pii: S0168-3659(15)30094-8. doi: 10.1016/j.jconrel.2015.08.051.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 66812 | pTK305 | IVT vector for Fluc mRNA |