Addgene: TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells.

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TET1 is a maintenance DNA demethylase that prevents methylation spreading in differentiated cells.
Jin C, Lu Y, Jelinek J, Liang S, Estecio MR, Barton MC, Issa JP
Nucleic Acids Res. 2014 Jun;42(11):6956-71. doi: 10.1093/nar/gku372. Epub 2014 May 29. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
83568	pIRES-hrGFP II-TET1	Expresses TET1 in mammalian cells
83569	pIRES-hrGFP II-mTET1	Expresses TET1 with a mutated catalytic domain in mammalian cells
83570	pIRES-hrGFP II-TET1_CD	Expresses the catalytic domain of TET1 in mammalian cells
83571	pIRES-hrGFP II-mTET1_CD	Expresses a mutant catalytic domain of TET1 in mammalian cells

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