Addgene: Editing DNA Methylation in the Mammalian Genome.

This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

We will increase some of our prices at 12:00 AM ET on April 1, 2023. Be sure to complete your order before this time to take advantage of current prices. See the new prices and get more information or speak with our friendly support team.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected] Learn more

Editing DNA Methylation in the Mammalian Genome.
Liu XS, Wu H, Ji X, Stelzer Y, Wu X, Czauderna S, Shu J, Dadon D, Young RA, Jaenisch R
Cell. 2016 Sep 22;167(1):233-247.e17. doi: 10.1016/j.cell.2016.08.056. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
84475	Fuw-dCas9-Tet1CD	Lentiviral construct to express dCas9 fused with the catalytic domain of Tet1	Loading...
84476	Fuw-dCas9-Dnmt3a	Lentiviral construct to express dCas9 fused with Dnmt3a	Loading...
84477	pgRNA-modified	guide RNA expression lentiviral construct	Loading...
84478	Fuw-dCas9-Dnmt3a_IM	Lentiviral construct to express dCas9 fused with an inactive Dnmt3a catalytic domain (E664A, E756A)	Loading...
84479	Fuw-dCas9-Tet1CD_IM	Lentiviral construct to express dCas9 fused with an inactive catalytic domain of Tet1 (H1672Y, D1674A)	Loading...
84569	Fuw-dCas9-Dnmt3a-P2A-tagBFP	Lentiviral construct to express dCas9 fused with Dnmt3a-P2A-tagBFP	Loading...
84570	138-dCas9-Dnmt3a	PiggyBac transposon system construct with dCas9-Dnmt3a	Loading...

Recombinant Antibodies from Article