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Ectodomain cleavage of FLT1 regulates receptor activation and function and is not required for its downstream intracellular cleavage.

Raikwar NS, Liu KZ, Thomas CP
Exp Cell Res. 2016 May 15;344(1):103-11. doi: 10.1016/j.yexcr.2016.03.020. Epub 2016 Mar 23. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
86034FLT1-KDRchimera of human VEGFR1 extracellular domain with the TMD fused to the intracellular domain of VEGFR2
86035hFLT1 delta 754-763human VEGFR1 with a 10 amino acid deletion in EC close to TM domain
86038hFlt1 V767Ahuman VEGFR1 with V to A mutation at position 767

Antibodies from Article