Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway.
Lessard F, Igelmann S, Trahan C, Huot G, Saint-Germain E, Mignacca L, Del Toro N, Lopes-Paciencia S, Le Calve B, Montero M, Deschenes-Simard X, Bury M, Moiseeva O, Rowell MC, Zorca CE, Zenklusen D, Brakier-Gingras L, Bourdeau V, Oeffinger M, Ferbeyre G
Nat Cell Biol. 2018 Jul;20(7):789-799. doi: 10.1038/s41556-018-0127-y. Epub 2018 Jun 25. PubMed Article
Lessard F, Igelmann S, Trahan C, Huot G, Saint-Germain E, Mignacca L, Del Toro N, Lopes-Paciencia S, Le Calve B, Montero M, Deschenes-Simard X, Bury M, Moiseeva O, Rowell MC, Zorca CE, Zenklusen D, Brakier-Gingras L, Bourdeau V, Oeffinger M, Ferbeyre G
Nat Cell Biol. 2018 Jul;20(7):789-799. doi: 10.1038/s41556-018-0127-y. Epub 2018 Jun 25. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 122235 | pBABE-RPS14(WT)-Myc | expresses RPS14 protein with a Myc tag in mammalian cells (puro resistance) |
| 122236 | MSCV-RPS14(WT)-Myc | expresses RPS14 protein with a Myc tag in mammalian cells (hygro resistance) |
| 122296 | pBABE-RSLID1(WT) | expresses RSL1D1 protein in mammalian cells (puro resistance) |
| 122297 | pcDNA3-FLAG-RPS14(WT) | expresses RPS14 protein with a flag tag |
| 122298 | pcDNA3-FLAG-RPS14(2-88) | expresses a part of RPS14 protein with a flag tag |
| 122299 | pcDNA3-FLAG-RPS14(89-151) | expresses a part of RPS14 protein with a flag tag |
| 122300 | pcDNA3-Myc-CyclinD1(WT) | expresses Cyclin D1 protein with a Myc tag |
| 122301 | pcDNA3.1-3xFLAG-RSL1D1(WT) | expresses RSL1D1 protein with a flag tag |