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MCART1/SLC25A51 is required for mitochondrial NAD transport.
Kory N, Uit de Bos J, van der Rijt S, Jankovic N, Gura M, Arp N, Pena IA, Prakash G, Chan SH, Kunchok T, Lewis CA, Sabatini DM
Sci Adv. 2020 Oct 21;6(43):eabe5310. doi: 10.1126/sciadv.abe5310. Print 2020 Oct. PubMed Article

Plasmids from Article

ID Plasmid Purpose
133247pMXs_FLAG-MCART1Express FLAG-tagged MCART1 in mammalian cells
133248pMXs_FLAG-MCART1K91AExpress FLAG-tagged MCART1K91A in mammalian cells
133249pMXs_FLAG-MCART1Q90AExpress FLAG-tagged MCART1Q90A in mammalian cells
133250pMXs_FLAG-MCART2Express FLAG-tagged MCART2 in mammalian cells
133251pMXs_FLAG-MCART6Express FLAG-tagged MCART6 in mammalian cells
133252pMXs_FLAG-MCART1R182AExpress FLAG-tagged MCART1R182A in mammalian cells
133253pMXs_MCART1Express untagged MCART1 in mammalian cells
133254pMXs_FLAG-NDT1Express FLAG-tagged NDT1 in mammalian cells
133255pMXs_FLAG-NDT2Express FLAG-tagged NDT2 in mammalian cells
133256pMXs_FLAG-ODC1Express FLAG-tagged ODC1 in mammalian cells
133257pMXs_FLAG-ODC2Express FLAG-tagged ODC2 in mammalian cells
133258pMXs_FLAG-GGC1Express FLAG-tagged GGC1 in mammalian cells
133259pMXs_FLAG-NMNAT1Express FLAG-tagged NMNAT1 in mammalian cells
133260pMXs_FLAG-NMNAT2Express FLAG-tagged NMNAT2 in mammalian cells
133261pMXs_NMNAT3-FLAGExpress FLAG-tagged NMNAT3 in mammalian cells
136371pMXs_FLAG-MFTExpression in mammalian cells
138408pMXs_FLAG-MCART1R278AExpress FLAG-tagged MCART1R278A in mammalian cells
138409pMXs_FLAG-MCART1W283AExpress FLAG-tagged MCART1W283A in mammalian cells
140591YCplac33-NAT_MCART1Express MCART1 in S. cerevisiae
140592YCplac33-NAT_MCART1K91AExpress MCART1K91A in S. cerevisiae
140593YCplac33-NAT_NDT1Express NDT1 in S. cerevisiae
140594YCplac33-NATExpression in S. cerevisiae

Antibodies from Article