Optogenetic control of cofilin and alphaTAT in living cells using Z-lock.
Stone OJ, Pankow N, Liu B, Sharma VP, Eddy RJ, Wang H, Putz AT, Teets FD, Kuhlman B, Condeelis JS, Hahn KM
Nat Chem Biol. 2019 Dec;15(12):1183-1190. doi: 10.1038/s41589-019-0405-4. Epub 2019 Nov 18. PubMed Article
Stone OJ, Pankow N, Liu B, Sharma VP, Eddy RJ, Wang H, Putz AT, Teets FD, Kuhlman B, Condeelis JS, Hahn KM
Nat Chem Biol. 2019 Dec;15(12):1183-1190. doi: 10.1038/s41589-019-0405-4. Epub 2019 Nov 18. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 141135 | E. coli expression: Z-lock cofilin dark state mutant | a control for optogenetic cofilin analog |
| 141136 | Mammalian expression: Z-lock cofilin dark state mutant | a control for optogenetic cofilin analog |
| 141137 | Z-lock cofilin | controlling the actin-severing ability of cofilin with light |
| 175290 | Z-lock αTAT | light-controlled analog of the alpha-tubulin acetylase αTAT |