Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant.
Deng X, Garcia-Knight MA, Khalid MM, Servellita V, Wang C, Morris MK, Sotomayor-Gonzalez A, Glasner DR, Reyes KR, Gliwa AS, Reddy NP, Sanchez San Martin C, Federman S, Cheng J, Balcerek J, Taylor J, Streithorst JA, Miller S, Sreekumar B, Chen PY, Schulze-Gahmen U, Taha TY, Hayashi JM, Simoneau CR, Kumar GR, McMahon S, Lidsky PV, Xiao Y, Hemarajata P, Green NM, Espinosa A, Kath C, Haw M, Bell J, Hacker JK, Hanson C, Wadford DA, Anaya C, Ferguson D, Frankino PA, Shivram H, Lareau LF, Wyman SK, Ott M, Andino R, Chiu CY
Cell. 2021 Jun 24;184(13):3426-3437.e8. doi: 10.1016/j.cell.2021.04.025. Epub 2021 Apr 20.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 177961 | CoV2-Spike-D614G-Alpha | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (Alpha: del69,70, del144, D614G, N501Y, A570D, P681H, T716I, S982A, D1118H) |
| 177962 | CoV2-Spike-D614G-Beta | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (Beta: K417N, E484K, N501Y, D614G) |
| 177963 | CoV2-Spike-D614G-Gamma | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (Gamma: L13F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F) |
| 177964 | CoV2-Spike-D614G-Epsilon | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (Epsilon: S13I, W152C, L452R, D614G) |
| 177965 | CoV2-Spike-D614G-S13I | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, S13I) |
| 177966 | CoV2-Spike-D614G-T20N | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, T20N) |
| 177967 | CoV2-Spike-D614G-P26S | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, P26S) |
| 177968 | CoV2-Spike-D614G-W152C | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, W152C) |
| 177969 | CoV2-Spike-D614G-K417N | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, K417N) |
| 177970 | CoV2-Spike-D614G-N439K | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, N439K) |
| 177971 | CoV2-Spike-D614G-L452R | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, L452R) |
| 177972 | CoV2-Spike-D614G-S477N | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, S477N) |
| 177973 | CoV2-Spike-D614G-P681H | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, P681H) |
| 177974 | CoV2-Spike-D614G-D1118H | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, D1118H) |
| 177975 | CoV2-Spike-D614G-N501Y | Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, N501Y) |