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Desmosomal cadherin tension loss in pemphigus vulgaris mediated by the inhibition of active RhoA at cell-cell adhesions.

Jin X, Rosenbohm J, Kim E, Safa BT, Moghaddam AO, Seiffert-Sinha K, Leiker M, Jones E, Zhai H, Baddam SR, Minnick G, Huo Y, Wahl JK 3rd, Meng F, Huang C, Lim JY, Conway DE, Sinha AA, Yang R
iScience. 2025 Jul 9;28(8):113081. doi: 10.1016/j.isci.2025.113081. eCollection 2025 Aug 15. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
182717pcdna 3.1 DSG-3 Tension Sensorexpresses DSG-3 TSmod
182718pcdna 3.1 DSG-3 Tailless Controlexpresses a truncated force-insensitive DSG-3 TSmod

Antibodies from Article