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Systemic administration of novel engineered AAV capsids facilitates enhanced transgene expression in the macaque CNS.
Stanton AC, Lagerborg KA, Tellez L, Krunnfusz A, King EM, Ye S, Solomon IH, Tabebordbar M, Sabeti PC
Med (N Y). 2022 Nov 15:S2666-6340(22)00456-1. doi: 10.1016/j.medj.2022.11.002.
PubMed Article

Plasmids from Article

ID Plasmid Purpose  
196679kiCAP-AAV-MDV1ARep/Cap plasmid for the production of MDV1A, an AAV capsid with CNS tropism in mice.
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196680kiCAP-AAV-MDV1BRep/Cap plasmid for the production of MDV1B, an AAV capsid with CNS tropism in mice.
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196681kiCAP-AAV-M.Mus.1Rep/Cap plasmid for the production of M.Mus.1, an AAV capsid with CNS tropism in mice.
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196682kiCAP-AAV-M.Mus.2Rep/Cap plasmid for the production of M.Mus.2, an AAV capsid with CNS tropism in mice.
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196683kiCAP-AAV-PAL1ARep/Cap plasmid for the production of PAL1A, an AAV capsid with CNS tropism in macaques.
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196684kiCAP-AAV-PAL1BRep/Cap plasmid for the production of PAL1B, an AAV capsid with CNS tropism in macaques.
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196685kiCAP-AAV-PAL1CRep/Cap plasmid for the production of PAL1C, an AAV capsid with CNS tropism in macaques.
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196686kiCAP-AAV-PAL1DRep/Cap plasmid for the production of PAL1D, an AAV capsid with CNS tropism in macaques.
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196687kiCAP-AAV-M.Fas.1Rep/Cap plasmid for the production of M.Fas.1, an AAV capsid with CNS tropism in macaques.
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196688kiCAP-AAV-M.Fas.2Rep/Cap plasmid for the production of M.Fas.2, an AAV capsid with CNS tropism in macaques.
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196689kiCAP-AAV-M.Fas.3Rep/Cap plasmid for the production of M.Fas.3, an AAV capsid with CNS tropism in macaques.
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196690kiCAP-AAV-M.Fas.4Rep/Cap plasmid for the production of M.Fas.4, an AAV capsid with CNS tropism in macaques.
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196691kiCAP-AAV-PAL2Rep/Cap plasmid for the production of PAL2, an AAV capsid with CNS tropism in macaques.
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Antibodies from Article