A comparison of viral strategies and model systems to target norepinephrine neurons in the locus coeruleus reveals high variability in transgene expression patterns.
Wissing C, Eschholz LS, Maheu M, Sauter K, Morellini F, Wiegert JS, Dieter A
PLoS Biol. 2025 Jul 7;23(7):e3003228. doi: 10.1371/journal.pbio.3003228. eCollection 2025 Jul.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 192587 | PRS_8-ChrimsonR-tdTomato | AAV-vector for optogenetic activation of noradrenergic neurons |
| 192589 | PRS_8-eGFP | AAV-vector for fluorescent labeling of noradrenergic neurons |
| 210399 | PRS_8-jRGECO1a | AAV-vector for fluorescent calcium measurements in the red spectrum from noradrenergic neurons |
| 210400 | PRS_8-GCaMP8m | AAV-vector for fluorescent calcium measurements in the green spectrum from noradrenergic neurons |