Loss of the lysosomal lipid flippase ATP10B leads to progressive dopaminergic neurodegeneration and parkinsonian motor deficits.
Sanchiz-Calvo M, Coccia E, Cawthorne C, Morrone Parfitt G, Torre-Muruzabal T, Tsafaras G, Van Laere K, Cabezudo D, Cascalho A, Van den Haute C, Vangheluwe P, Blanchard J, Bentea E, Baekelandt V
Acta Neuropathol. 2025 Jul 17;150(1):5. doi: 10.1007/s00401-025-02908-0.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 216391 | pAAV-CMVenh synapsin-intron-mCherry-1x miR5 Mm ATP10B | transfer plasmid for AAV vector production of mCherry and miR for Mm ATP10B |
| 216392 | pAAV-CMVenh synapsin-intron-mCherry-1x miR7 Rn ATP10B | transfer plasmid for AAV vector production of mCherry and miR for rat Rn ATP10B |
| 216393 | pAAV-CMVenh synapsin-intron-mCherry-1x miR30 SCR | transfer plasmid for AAV vector production of mCherry and miR scramble (no target) |