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High-throughput screening assay for PARP-HPF1 interaction inhibitors to affect DNA damage repair.

Dhakar SS, Galera-Prat A, Lehtio L
Sci Rep. 2024 Feb 16;14(1):3875. doi: 10.1038/s41598-024-54123-8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
216872PARP1-c009Bacterial expression vector for E. coli producing PARP1 catalytic protein (without Regulatory domain); with N-terminal CFP fusion
216873PARP2-c098Bacterial expression vector for E. coli producing PARP2 catalytic protein (without Regulatory domain); with N-terminal CFP fusion
216874HPF1-c004Bacterial expression vector for E. coli producing full length HPF1 protein with N-terminal YFP fusion

Antibodies from Article