The mTOR pathway genes MTOR, Rheb, Depdc5, Pten, and Tsc1 have convergent and divergent impacts on cortical neuron development and function.

Nguyen LH, Xu Y, Nair M, Bordey A
Elife. 2024 Feb 27;12:RP91010. doi: 10.7554/eLife.91010. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID	Plasmid	Purpose
254273	pCAG-Rheb-Y35L-tdTomato	Expresses Rheb-Y35L (activating mutation) and tdTomato
254274	pCAG-mTOR-S2215Y	Expresses mTOR-S2215Y (activating mutation)
254275	px330-TSC1	Knockout TSC1