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Inflammation Promotes Proteolytic Processing of the Prohormone Chromogranin A by Macrophages.

Ioannidis M, van Dijk H, Muntjewerff EM, Chirasani VR, Warner H, van den Dool W, Grijpstra P, Bianchi F, Mahata SK, van den Bogaart G
J Endocr Soc. 2025 May 15;9(7):bvaf090. doi: 10.1210/jendso/bvaf090. eCollection 2025 Jul. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
228569CHGA-eGFPExpresses GFP-tagged human Chromogranin A in mammalian cells
228570pcDNA3.1-FRET_PST-CExpressed a FRET sensor for determining proteolytic cleavage of the C-terminal side of Pancreastatin
228571pcDNA3.1-FRET_PST-NExpressed a FRET sensor for determining proteolytic cleavage of the N-terminal side of Pancreastatin
228572pcDNA3.1-FRET_CST-CExpressed a FRET sensor for determining proteolytic cleavage of the C-terminal side of Catestatin
228573pcDNA3.1-FRET_CST-NExpressed a FRET sensor for determining proteolytic cleavage of the N-terminal side of Catestatin

Antibodies from Article