Sensitive fluorescent biosensor reveals differential subcellular regulation of PKC.
Su Q, Zhang J, Lin W, Zhang JF, Newton AC, Mehta S, Yang J, Zhang J
Nat Chem Biol. 2024 Oct 11. doi: 10.1038/s41589-024-01758-3.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 236096 | pcDNA3-ExRai-CKAR2 | Enhanced excitation-ratiometric biosensor for monitoring Protein Kinase C activity in living cells. |
| 236097 | pcDNA3-Cyto-ExRai-CKAR2 | Cytosol-targeted enhanced excitation-ratiometric biosensor for monitoring Protein Kinase C activity in living cells. |
| 236098 | pcDNA3-PM-ExRai-CKAR2 | Plasma membrane-targeted enhanced excitation-ratiometric biosensor for monitoring Protein Kinase C activity in living cells. |
| 236099 | pcDNA3-ER-ExRai-CKAR2 | Enhanced excitation-ratiometric biosensor for monitoring Protein Kinase C activity in living cells, targeted to ER surface. |
| 236101 | pcDNA3-Par6-ExRai-CKAR2 | Subcellularly targeted enhanced excitation-ratiometric biosensor for monitoring Protein Kinase C activity in living cells for selective detection of aPKC activity within the Par complex. |