High throughput cryo-EM provides structural understanding for modulators of the lysosomal ion channel TRPML1
Judith Reeks, Pravin Mahajan, Mellissa Clark, Suzanna R. Cowan, Elena Di Daniel, Christopher P. Earl, Samantha Fisher, Rhian S. Holvey, Scott M. Jackson, Emyr Lloyd-Evans, Carmine M. Morgillo, Paul N. Mortenson, Marc O’Reilly, Caroline J. Richardson, Patrick Schöpf, Daniel M. Tams, Helen Waller-Evans, Simon E. Ward, Stuart Whibley, Pamela A. Williams, and Christopher N. Johnson
Structure, 2025
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
238303 | pACEMam2-TRPML1 | Expression of human TRPML1 in mammalian cells |