Unveiling sequence-agnostic mixed-chemical modification patterns for splice-switching oligonucleotides using the NATURA platform.
Tabaglio T, Agarwal T, Cher WY, Ow JR, Chew AK, Sun PYQ, Reddy Gurrampati RS, Lu H, Naidu P, Ng HK, Le Guezennec X, Ng SY, Lakshmanan M, Guccione E, Wee KB
Mol Ther Nucleic Acids. 2025 Jan 7;36(1):102422. doi: 10.1016/j.omtn.2024.102422. eCollection 2025 Mar 11.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 226553 | pRP.ABCA4 c.5461-10T | Minigene encoding the ABCA4 c.5461-10T mutation |
| 226554 | pRP.ATM c.7865C>T | Minigene encoding the ATM c.7865C>T mutation |
| 226555 | pRP.USH2A | Minigene encoding USH2A exon 13 and surrounding introns/exons |
| 226556 | pRP.CEP290 c.2991+1655A>G | Minigene encoding the CEP290 c.2991+1655A>G mutation |
| 226557 | pC2.4 | NATURA gene encoding plasmid |