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Extracellular vesicle-mediated delivery of genetic material for transformation and CRISPR/Cas9-based gene editing in Pneumocystis murina.

Sayson SG, Ashbaugh A, Bauer LC, Smulian AG
mBio. 2025 Sep 23:e0182525. doi: 10.1128/mbio.01825-25. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
241014pSS1-mNeongreenExpresses mNeongreen under control of Msg promoter
241015pSS2.1-Cas9-HH-gRNADhps-HDVCas9 expression cassette encoding a guide RNA targeting the Dhps locus, flanked by a hammerhead (HH) ribozyme at the 5′ end and a hepatitis delta virus (HDV) ribozyme at the 3′ end
241016pSS2.1-mNeongreenExpresses mNeongreen under control of Msg promoter

Antibodies from Article