The TRIP12 E3 ligase induces SWI/SNF component BRG1-beta-catenin interaction to promote Wnt signaling.
Kassel S, Yuan K, Bunnag N, Neitzel LR, Lu W, Schwarzkopf A, Maines B, Loberg MA, Xu G, Adams A, McCray AD, Cho A, Rockouski M, Orton G, Goldsmith L, Aronno MMA, Spencer ZT, Khan OM, Ye F, Williams C, Lebensohn AM, Rohatgi R, Wang X, Weiss VL, Hong CC, Kettenbach AN, Robbins DJ, Ahmed Y, Lee E
Nat Commun. 2025 Jun 5;16(1):5248. doi: 10.1038/s41467-025-60535-5.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 241814 | pCS2-Myc-TRIP12-CD | Expresses Myc-tagged catalytic dead TRIP12 in mammalian cells. |
| 241815 | pRP-BRG1-HA-SmBiT | Expresses HA-tagged and HiBiT-tagged BRG1 for use with the Promega HiBiT system |
| 241816 | pRP-B-catenin-V5-LgBiT | Expresses V5-tagged and LgBiT-tagged B-catenin for use with the Promega HiBiT system |
| 241817 | pcDNA3.1-Ub-Myc-LgBiT | Expresses Myc-tagged and LgBiT-tagged Ubiquitin for use with the Promega HiBiT system |
| 241818 | pGEX-TRIP12-HECT | Expesses GST-TRIP12 for protein purification |