Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC.
Liu S, Li L, Zhang F, Garcia-Corral M, Meyer K, Fortuna PRJ, van Sambeek B, Appleton E, Ng AHM, Khoshakhlagh P, Lu YR, Cameron J, Ramirez RN, Chen Y, Wu CT, Huang JY, Tan Y, Chao G, Aach J, Lim ET, Tam JM, Raychaudhuri S, Church GM
Nat Commun. 2025 Jun 10;16(1):5136. doi: 10.1038/s41467-025-59596-3.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 250291 | pBdox-SPI1-T2A-CEBPA-P2A-FLI1_BleoR | PiggyBac integration of 3 transcription factors (SPI1, CEBPA, FLI1) under a dox-inducible promoter |
| 250292 | pBdox-MEF2C-T2A-CEBPB-P2A-IRF8_PuroR | PiggyBac integration of 3 transcription factors (MEF2C, CEBPB, IRF8) under a dox-inducible promoter |