Cocaine chemogenetics blunts drug-seeking by synthetic physiology.
Gomez JL, Magnus CJ, Bonaventura J, Solis O, Curry FP, Levinstein MR, Budinich RC, Carlton ML, Ventriglia EN, Lam S, Wang L, Schoenborn I, Dunne W, Michaelides M, Sternson SM
Nature. 2025 Aug 27. doi: 10.1038/s41586-025-09427-8.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 242193 | pCAG coca-5HT3-IRES-GFP | Expression vector for cocaine-gated chemogenetic cation channel |
| 242195 | AAV Syn-FLEX-coca-5HT3-IRES-mCherry | Cre-dependent AAV vector for cocaine-gated chemogenetic cation channel |
| 242196 | AAV Syn-FLEX-coca-GlyR-IRES-mCherry | Cre-dependent AAV vector for cocaine-gated chemogenetic anion channel |
| 242197 | AAV Syn-coca-5HT3-IRES-mCherry | AAV vector for cocaine-gated chemogenetic cation channel |