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ADF/cofilin regulates actomyosin assembly through competitive inhibition of myosin II binding to F-actin.

Wiggan O, Shaw AE, DeLuca JG, Bamburg JR
Dev Cell. 2012 Mar 13;22(3):530-43. doi: 10.1016/j.devcel.2011.12.026. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
252616huCofilin WT SSRExpresses human wild-type cofilin (shRNA-resistant)
252617huCofilin K22Q SSR-mRFPExpresses shRNA resistant human cofilin with K22Q mutation that reduces nuclear uptake and serves as a cofilactin rod reporter

Antibodies from Article