De novo talin-1 variant L353F connects multifaceted clinical symptoms to alterations in talin-1 function.

Athale M, Ball N, Azizi L, Valenzuela I, Codina M, Martin-Nalda A, Mykuliak VV, Rahikainen R, Goult BT, Turkki P, Hytonen VP
Biochem J. 2025 Sep 17;482(18):1337-1352. doi: 10.1042/BCJ20253128. PubMed Article

Plasmids from Article

ID	Plasmid	Purpose
247087	pTalin.L353F.EGFP	Expression plasmid for the full length Talin1 containing L353F missense mutation. The EGFP is present at the C-terminal end.
247088	pMinitalin.L353F.EGFP	Expression plasmid for the minitalin containing L353F missense mutation. The EGFP is present at the C-terminal end.